ENSMUSG00000029381


Mus musculus

Features
Gene ID: ENSMUSG00000029381
  
Biological name :Shroom3
  
Synonyms : Shroom3 / shroom family member 3
  
Possible biological names infered from orthology : Q8TF72
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: E2
Gene start: 92683435
Gene end: 92965318
  
Corresponding Affymetrix probe sets: 10523260 (MoGene1.0st)   1422629_s_at (Mouse Genome 430 2.0 Array)   1432377_x_at (Mouse Genome 430 2.0 Array)   1451854_a_at (Mouse Genome 430 2.0 Array)   1453714_a_at (Mouse Genome 430 2.0 Array)   1454211_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108677
Ensembl peptide - ENSMUSP00000153516
Ensembl peptide - ENSMUSP00000133690
Ensembl peptide - ENSMUSP00000130419
Ensembl peptide - ENSMUSP00000108678
Ensembl peptide - ENSMUSP00000108674
NCBI entrez gene - 27428     See in Manteia.
MGI - MGI:1351655
RefSeq - XM_006534968
RefSeq - NM_001077595
RefSeq - NM_001077596
RefSeq - NM_015756
RefSeq - XM_006534966
RefSeq Peptide - NP_001071063
RefSeq Peptide - NP_056571
RefSeq Peptide - NP_001071064
swissprot - A0A0R4J1H8
swissprot - G3UXH3
swissprot - E9Q6I3
swissprot - E9QMY5
swissprot - A0A286YDQ8
Ensembl - ENSMUSG00000029381
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shroom3ENSDARG00000102180Danio rerio
 ENSGALG00000042427Gallus gallus
 Q8TF72ENSG00000138771Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2ALU4 / Shroom2 / shroom family member 2 / Q13796*ENSMUSG0000004518023
Q1W617 / Shroom4 / Protein Shroom4 / Q9ULL8* / shroom family member 4*ENSMUSG0000006827019
Q5SX79 / Shroom1 / shroom family member 1 / Q2M3G4*ENSMUSG0000001838710


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR014799  Apx/Shrm Domain 2
 IPR014800  Apx/Shrm Domain 1
 IPR027685  Shroom family
 IPR030494  Shroom3
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0002064 epithelial cell development IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000075 absent neurocranium "missing bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0000108 midline facial cleft "incomplete merging or fusion of the tissues normally uniting to form the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Shroom3m1Nisw/Shroom3m1Nisw
Genetic Background: 129S1.B6-Shroom3m1Nisw

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0000930 wavy neural tube "undulations in the embryonic neural tube" [J:37888]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0003385 abnormal body wall "malformation in the external portion of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Shroom3m1Nisw/Shroom3m1Nisw
Genetic Background: 129S1.B6-Shroom3m1Nisw

 MP:0005155 herniated intestine "protrusion of any portion of the intestine from its normal anatomical position" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0008797 facial cleft "a cleft resulting from incomplete merging or fusion of any of the embryonic facial processes that normally unite to form the face" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Shroom3m1Nisw/Shroom3m1Nisw
Genetic Background: 129S1.B6-Shroom3m1Nisw

 MP:0010912 herniated liver "protrusion of any portion of the liver from its normal anatomical position" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Shc2tm1Paw/Shc2tm1Paw,Shc3tm1Paw/Shc3tm1Paw
Genetic Background: involves: 129/Sv

Allelic Composition: Shroom3m1Nisw/Shroom3m1Nisw
Genetic Background: 129S1.B6-Shroom3m1Nisw

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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