ENSG00000148344


Homo sapiens

Features
Gene ID: ENSG00000148344
  
Biological name :PTGES
  
Synonyms : O14684 / prostaglandin E synthase / PTGES
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.11
Gene start: 129738331
Gene end: 129753047
  
Corresponding Affymetrix probe sets: 207388_s_at (Human Genome U133 Plus 2.0 Array)   210367_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000342385
NCBI entrez gene - 9536     See in Manteia.
OMIM - 605172
RefSeq - NM_004878
RefSeq - XM_011519210
RefSeq Peptide - NP_004869
swissprot - O14684
Ensembl - ENSG00000148344
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptgesENSDARG00000020136Danio rerio
 PTGESENSGALG00000038013Gallus gallus
 PtgesENSMUSG00000050737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MGST1 / P10620 / microsomal glutathione S-transferase 1ENSG0000000839438


Protein motifs (from Interpro)
Interpro ID Name
 IPR001129  Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
 IPR023352  Membrane associated eicosanoid/glutathione metabolism-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IEA
 biological_processGO:0002526 acute inflammatory response IEA
 biological_processGO:0002544 chronic inflammatory response IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006693 prostaglandin metabolic process TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0019371 cyclooxygenase pathway TAS
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0051592 response to calcium ion IEA
 cellular_componentGO:0005641 nuclear envelope lumen IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0043295 glutathione binding IDA
 molecular_functionGO:0050220 prostaglandin-E synthase activity EXP


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000148344 PTGES / O14684 / prostaglandin E synthase  / complex






 

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