ENSG00000148357


Homo sapiens

Features
Gene ID: ENSG00000148357
  
Biological name :HMCN2
  
Synonyms : hemicentin 2 / HMCN2 / Q8NDA2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 130265882
Gene end: 130434123
  
Corresponding Affymetrix probe sets: 1563532_at (Human Genome U133 Plus 2.0 Array)   1564117_at (Human Genome U133 Plus 2.0 Array)   235932_x_at (Human Genome U133 Plus 2.0 Array)   241650_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481543
Ensembl peptide - ENSP00000485357
Ensembl peptide - ENSP00000485578
Ensembl peptide - ENSP00000387564
RefSeq - XM_011518468
RefSeq - XM_011518467
RefSeq - XM_011518466
RefSeq - XM_011518465
RefSeq - XM_017014585
RefSeq - XM_011518469
RefSeq - NM_001291815
RefSeq Peptide - NP_001278744
swissprot - Q8NDA2
swissprot - A0A087WY63
swissprot - H0Y3X1
swissprot - A0A096LPG1
Ensembl - ENSG00000148357
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmcn2ENSDARG00000079327Danio rerio
 Hmcn2ENSMUSG00000055632Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMCN1 / Q96RW7 / hemicentin 1ENSG0000014334144
TTN / titin / Q8WZ42ENSG0000015565719
OBSCN / Q5VST9 / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEFENSG0000015435819
MXRA5 / Q9NR99 / matrix remodeling associated 5ENSG0000010182511
IGSF10 / Q6WRI0 / immunoglobulin superfamily member 10ENSG0000015258010
OBSL1 / O75147 / obscurin like 1ENSG000001240067
PALLD / Q8WX93 / palladin, cytoskeletal associated proteinENSG000001291164
MYPN / Q86TC9 / myopalladinENSG000001383474
MYOT / Q9UBF9 / myotilinENSG000001207292


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR006605  G2 nidogen/fibulin G2F
 IPR007110  Immunoglobulin-like domain
 IPR009017  Green fluorescent protein
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR009138  Neural cell adhesion
 IPR013032  EGF-like, conserved site
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain
 IPR032984  Hemicentin-2
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006939 smooth muscle contraction IBA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0030335 positive regulation of cell migration IBA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0032154 cleavage furrow IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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