ENSG00000148935


Homo sapiens

Features
Gene ID: ENSG00000148935
  
Biological name :GAS2
  
Synonyms : GAS2 / growth arrest specific 2 / O43903
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p14.3
Gene start: 22625642
Gene end: 22813055
  
Corresponding Affymetrix probe sets: 205848_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432584
Ensembl peptide - ENSP00000432026
Ensembl peptide - ENSP00000433182
Ensembl peptide - ENSP00000485708
Ensembl peptide - ENSP00000435946
Ensembl peptide - ENSP00000434478
Ensembl peptide - ENSP00000278187
Ensembl peptide - ENSP00000401145
NCBI entrez gene - 2620     See in Manteia.
OMIM - 602835
RefSeq - XM_017017532
RefSeq - XM_011519971
RefSeq - XM_011519972
RefSeq - XM_011519975
RefSeq - XM_011519978
RefSeq - XM_017017528
RefSeq - XM_017017529
RefSeq - XM_017017530
RefSeq - XM_017017531
RefSeq - NM_001143830
RefSeq - NM_005256
RefSeq - NM_177553
RefSeq Peptide - NP_808221
RefSeq Peptide - NP_001137302
RefSeq Peptide - NP_005247
swissprot - E9PRR5
swissprot - E9PM28
swissprot - O43903
swissprot - E9PQ74
swissprot - E9PQ37
Ensembl - ENSG00000148935
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gas2aENSDARG00000001259Danio rerio
 gas2bENSDARG00000036152Danio rerio
 GAS2ENSGALG00000003655Gallus gallus
 Gas2ENSMUSG00000030498Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GAS2L3 / Q86XJ1 / growth arrest specific 2 like 3ENSG0000013935458
GAS2L2 / Q8NHY3 / growth arrest specific 2 like 2ENSG0000027076535
GAS2L1 / Q99501 / growth arrest specific 2 like 1ENSG0000018534034


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR003108  GAR domain
 IPR029929  Growth arrest-specific protein 2
 IPR029932  GAS2-like protein 3
 IPR036534  GAR domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
Caspase-mediated cleavage of cytoskeletal proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164305 CASP3 / P42574 / caspase 3  / reaction
 ENSG00000165806 CASP7 / P55210 / caspase 7  / reaction






 

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contact: otassy@igbmc.fr