ENSMUSG00000030498


Mus musculus

Features
Gene ID: ENSMUSG00000030498
  
Biological name :Gas2
  
Synonyms : Gas2 / Mus musculus growth arrest specific 2 (Gas2), transcript variant 2, mRNA. / P11862
  
Possible biological names infered from orthology : growth arrest specific 2 / O43903
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B4
Gene start: 51862015
Gene end: 51994975
  
Corresponding Affymetrix probe sets: 10553521 (MoGene1.0st)   1429147_at (Mouse Genome 430 2.0 Array)   1450112_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053514
Ensembl peptide - ENSMUSP00000114743
Ensembl peptide - ENSMUSP00000117367
Ensembl peptide - ENSMUSP00000146537
Ensembl peptide - ENSMUSP00000103217
NCBI entrez gene - 14453     See in Manteia.
MGI - MGI:95657
RefSeq - XM_017321982
RefSeq - XM_011250796
RefSeq - XM_011250797
RefSeq - XM_017321979
RefSeq - XM_017321980
RefSeq - XM_017321981
RefSeq - NM_001330607
RefSeq - NM_008087
RefSeq - XM_006540618
RefSeq - XM_006540619
RefSeq - XM_006540620
RefSeq - XM_006540621
RefSeq - XM_006540622
RefSeq - XM_006540623
RefSeq - XM_006540624
RefSeq - XM_006540625
RefSeq - XM_006540626
RefSeq - XM_006540627
RefSeq Peptide - NP_001317536
RefSeq Peptide - NP_032113
swissprot - D6RDR2
swissprot - P11862
swissprot - D3Z503
Ensembl - ENSMUSG00000030498
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gas2aENSDARG00000001259Danio rerio
 gas2bENSDARG00000036152Danio rerio
 GAS2ENSGALG00000003655Gallus gallus
 GAS2ENSG00000148935Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gas2l3 / growth arrest specific 2 like 3 / Q86XJ1*ENSMUSG0000007480258
Gas2l2 / Q5SSG4 / GAS2-like protein 2 / Q8NHY3* / growth arrest specific 2 like 2*ENSMUSG0000002068636
Gas2l1 / Q8JZP9 / GAS2-like protein 1 / Q99501* / growth arrest specific 2 like 1*ENSMUSG0000003420134


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR003108  GAR domain
 IPR029929  Growth arrest-specific protein 2
 IPR029932  GAS2-like protein 3
 IPR036534  GAR domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
Caspase-mediated cleavage of cytoskeletal proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025076 Casp7 / P97864 / Caspase-7 Caspase-7 subunit p20 Caspase-7 subunit p11 / P55210* / caspase 7*  / reaction
 ENSMUSG00000031628 Casp3 / P70677 / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12 / P42574* / caspase 3*  / reaction






 

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