ENSG00000149212


Homo sapiens

Features
Gene ID: ENSG00000149212
  
Biological name :SESN3
  
Synonyms : P58005 / SESN3 / sestrin 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q21
Gene start: 95165513
Gene end: 95232541
  
Corresponding Affymetrix probe sets: 1553869_at (Human Genome U133 Plus 2.0 Array)   225123_at (Human Genome U133 Plus 2.0 Array)   235150_at (Human Genome U133 Plus 2.0 Array)   235683_at (Human Genome U133 Plus 2.0 Array)   235684_s_at (Human Genome U133 Plus 2.0 Array)   242899_at (Human Genome U133 Plus 2.0 Array)   242906_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000439580
Ensembl peptide - ENSP00000489281
Ensembl peptide - ENSP00000441927
Ensembl peptide - ENSP00000278499
Ensembl peptide - ENSP00000407008
NCBI entrez gene - 143686     See in Manteia.
OMIM - 607768
RefSeq - XM_011542614
RefSeq - NM_001271594
RefSeq - NM_144665
RefSeq Peptide - NP_001258523
RefSeq Peptide - NP_653266
swissprot - A0A0U1RR17
swissprot - F5H1K7
swissprot - P58005
Ensembl - ENSG00000149212
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sesn3ENSDARG00000015822Danio rerio
 ENSGALG00000017204Gallus gallus
 Sesn3ENSMUSG00000032009Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SESN1 / Q9Y6P5 / sestrin 1ENSG0000008054659
SESN2 / P58004 / sestrin 2ENSG0000013076653


Protein motifs (from Interpro)
Interpro ID Name
 IPR006730  Sestrin
 IPR029032  AhpD-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0034198 cellular response to amino acid starvation IMP
 biological_processGO:0038203 TORC2 signaling IEA
 biological_processGO:0042149 cellular response to glucose starvation IMP
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0051896 regulation of protein kinase B signaling IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:1901031 regulation of response to reactive oxygen species IEA
 biological_processGO:1904262 negative regulation of TORC1 signaling IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031932 TORC2 complex IEA
 cellular_componentGO:0061700 GATOR2 complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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