ENSG00000149428


Homo sapiens

Features
Gene ID: ENSG00000149428
  
Biological name :HYOU1
  
Synonyms : HYOU1 / hypoxia up-regulated 1 / Q9Y4L1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 119044189
Gene end: 119057202
  
Corresponding Affymetrix probe sets: 200825_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479845
Ensembl peptide - ENSP00000484622
Ensembl peptide - ENSP00000484186
Ensembl peptide - ENSP00000483106
Ensembl peptide - ENSP00000482199
Ensembl peptide - ENSP00000480248
Ensembl peptide - ENSP00000480150
Ensembl peptide - ENSP00000431874
Ensembl peptide - ENSP00000442727
Ensembl peptide - ENSP00000462951
Ensembl peptide - ENSP00000463318
Ensembl peptide - ENSP00000463515
Ensembl peptide - ENSP00000463742
Ensembl peptide - ENSP00000464026
Ensembl peptide - ENSP00000467866
NCBI entrez gene - 10525     See in Manteia.
OMIM - 601746
RefSeq - XM_017017097
RefSeq - NM_001130991
RefSeq - NM_006389
RefSeq - XM_005271392
RefSeq - XM_005271393
RefSeq - XM_005271394
RefSeq - XM_017017095
RefSeq - XM_017017096
RefSeq Peptide - NP_001124463
RefSeq Peptide - NP_006380
swissprot - K7EQK2
swissprot - Q9Y4L1
swissprot - E9PJ21
swissprot - Q9BST8
swissprot - A0A087X054
swissprot - A0A087WWI4
swissprot - A0A087WW13
swissprot - A0A087X214
swissprot - J3KSR2
swissprot - J3KTF1
swissprot - J3QLE9
swissprot - J3QL06
swissprot - J3QQH7
Ensembl - ENSG00000149428
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hyou1ENSDARG00000013670Danio rerio
 HYOU1ENSGALG00000007659Gallus gallus
 Hyou1ENSMUSG00000032115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPA4 / P34932 / heat shock protein family A (Hsp70) member 4ENSG0000017060624
HSPA4L / O95757 / heat shock protein family A (Hsp70) member 4 likeENSG0000016407023
HSPH1 / Q92598 / heat shock protein family H (Hsp110) member 1ENSG0000012069422


Protein motifs (from Interpro)
Interpro ID Name
 IPR013126  Heat shock protein 70 family
 IPR018181  Heat shock protein 70, conserved site
 IPR029047  Heat shock protein 70kD, peptide-binding domain superfamily
 IPR029048  Heat shock protein 70kD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IDA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0034976 response to endoplasmic reticulum stress IEP
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0071456 cellular response to hypoxia IEP
 biological_processGO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway IDA
 biological_processGO:1903382 negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005783 endoplasmic reticulum NAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005790 smooth endoplasmic reticulum ISS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0034663 endoplasmic reticulum chaperone complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071682 endocytic vesicle lumen TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0051087 chaperone binding ISS


Pathways (from Reactome)
Pathway description
Scavenging by Class F Receptors
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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