ENSG00000170606


Homo sapiens

Features
Gene ID: ENSG00000170606
  
Biological name :HSPA4
  
Synonyms : heat shock protein family A (Hsp70) member 4 / HSPA4 / P34932
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q31.1
Gene start: 133051962
Gene end: 133106449
  
Corresponding Affymetrix probe sets: 208814_at (Human Genome U133 Plus 2.0 Array)   208815_x_at (Human Genome U133 Plus 2.0 Array)   211015_s_at (Human Genome U133 Plus 2.0 Array)   211016_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302961
Ensembl peptide - ENSP00000481686
Ensembl peptide - ENSP00000478102
NCBI entrez gene - 3308     See in Manteia.
OMIM - 601113
RefSeq - NM_002154
RefSeq Peptide - NP_002145
swissprot - A0A087WYC1
swissprot - A0A087WTS8
swissprot - P34932
Ensembl - ENSG00000170606
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hspa4aENSDARG00000004754Danio rerio
 hspa4bENSDARG00000018989Danio rerio
 HSPA4ENSGALG00000040882Gallus gallus
 Hspa4ENSMUSG00000020361Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPA4L / O95757 / heat shock protein family A (Hsp70) member 4 likeENSG0000016407063
HSPH1 / Q92598 / heat shock protein family H (Hsp110) member 1ENSG0000012069461
HYOU1 / Q9Y4L1 / hypoxia up-regulated 1ENSG0000014942828


Protein motifs (from Interpro)
Interpro ID Name
 IPR013126  Heat shock protein 70 family
 IPR018181  Heat shock protein 70, conserved site
 IPR029047  Heat shock protein 70kD, peptide-binding domain superfamily
 IPR029048  Heat shock protein 70kD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006986 response to unfolded protein NAS
 biological_processGO:0045040 protein import into mitochondrial outer membrane IDA
 biological_processGO:0051131 chaperone-mediated protein complex assembly IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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