ENSG00000149488


Homo sapiens

Features
Gene ID: ENSG00000149488
  
Biological name :TMC2
  
Synonyms : Q8TDI7 / TMC2 / transmembrane channel like 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p13
Gene start: 2536607
Gene end: 2641784
  
Corresponding Affymetrix probe sets: 1553019_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351732
Ensembl peptide - ENSP00000495303
NCBI entrez gene - 117532     See in Manteia.
OMIM - 606707
RefSeq - XM_005260660
RefSeq - NM_080751
RefSeq Peptide - NP_542789
swissprot - Q8TDI7
Ensembl - ENSG00000149488
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmc2aENSDARG00000033104Danio rerio
 tmc2bENSDARG00000030311Danio rerio
 TMC2ENSGALG00000042706Gallus gallus
 Tmc2ENSMUSG00000060332Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TMC1 / Q8TDI8 / transmembrane channel like 1ENSG0000016509148
TMC3 / Q7Z5M5 / transmembrane channel like 3ENSG0000018886937
TMC7 / Q7Z402 / transmembrane channel like 7ENSG0000017053718
TMC6 / Q7Z403 / transmembrane channel like 6ENSG0000014152417
TMC5 / Q6UXY8 / transmembrane channel like 5ENSG0000010353417
TMC8 / Q8IU68 / transmembrane channel like 8ENSG0000016789517
TMC4 / transmembrane channel like 4ENSG0000016760816


Protein motifs (from Interpro)
Interpro ID Name
 IPR012496  TMC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0050910 detection of mechanical stimulus involved in sensory perception of sound IEA
 biological_processGO:0060005 vestibular reflex IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:1903169 regulation of calcium ion transmembrane transport IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032426 stereocilium tip IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0008381 mechanosensitive ion channel activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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