ENSG00000152086


Homo sapiens

Features
Gene ID: ENSG00000152086
  
Biological name :TUBA3E
  
Synonyms : Q6PEY2 / TUBA3E / tubulin alpha 3e
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q21.1
Gene start: 130191743
Gene end: 130198461
  
Corresponding Affymetrix probe sets: 216323_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000318197
NCBI entrez gene - 112714     See in Manteia.
RefSeq - NM_207312
RefSeq Peptide - NP_997195
swissprot - Q6PEY2
Ensembl - ENSG00000152086
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tuba7lENSDARG00000104643Danio rerio
 tuba8lENSDARG00000042708Danio rerio
 ENSGALG00000006241Gallus gallus
 P05214ENSMUSG00000067338Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q13748 / TUBA3C / tubulin alpha 3cENSG0000019803399
Q13748 / TUBA3D / tubulin alpha 3dENSG0000007588699
P68363 / TUBA1B / tubulin alpha 1bENSG0000012341696
Q71U36 / TUBA1A / tubulin alpha 1aENSG0000016755296
Q9BQE3 / TUBA1C / tubulin alpha 1cENSG0000016755395
P68366 / TUBA4A / tubulin alpha 4aENSG0000012782493
Q9H853 / TUBA4B / tubulin alpha 4bENSG0000024391038


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002452  Alpha tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Cilium Assembly
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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