ENSG00000152332


Homo sapiens

Features
Gene ID: ENSG00000152332
  
Biological name :UHMK1
  
Synonyms : Q8TAS1 / U2AF homology motif kinase 1 / UHMK1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.3
Gene start: 162497251
Gene end: 162529629
  
Corresponding Affymetrix probe sets: 1552656_s_at (Human Genome U133 Plus 2.0 Array)   224691_at (Human Genome U133 Plus 2.0 Array)   227740_at (Human Genome U133 Plus 2.0 Array)   235003_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420270
Ensembl peptide - ENSP00000441226
Ensembl peptide - ENSP00000446416
NCBI entrez gene - 127933     See in Manteia.
OMIM - 608849
RefSeq - NM_144624
RefSeq - NM_001184763
RefSeq - NM_175866
RefSeq Peptide - NP_001171692
RefSeq Peptide - NP_653225
RefSeq Peptide - NP_787062
swissprot - Q8TAS1
Ensembl - ENSG00000152332
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uhmk1ENSDARG00000059575Danio rerio
 UHMK1ENSGALG00000002734Gallus gallus
 Uhmk1ENSMUSG00000026667Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
U2AF2 / P26368 / U2 small nuclear RNA auxiliary factor 2ENSG0000006324418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR034371  UHMK1, RNA recognition motif
 IPR034372  Serine/threonine-protein kinase Kist
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007050 cell cycle arrest IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0031175 neuron projection development ISS
 biological_processGO:0045948 positive regulation of translational initiation ISS
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046825 regulation of protein export from nucleus IDA
 cellular_componentGO:0000243 commitment complex IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016607 nuclear speck IBA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0032839 dendrite cytoplasm ISS
 cellular_componentGO:0035770 ribonucleoprotein granule IBA
 cellular_componentGO:0071004 U2-type prespliceosome IBA
 cellular_componentGO:0071598 neuronal ribonucleoprotein granule ISS
 cellular_componentGO:0089701 U2AF IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IC
 molecular_functionGO:0008187 poly-pyrimidine tract binding IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IC
 molecular_functionGO:0030628 pre-mRNA 3"-splice site binding IBA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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