ENSG00000152778


Homo sapiens

Features
Gene ID: ENSG00000152778
  
Biological name :IFIT5
  
Synonyms : IFIT5 / interferon induced protein with tetratricopeptide repeats 5 / Q13325
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.31
Gene start: 89414586
Gene end: 89421001
  
Corresponding Affymetrix probe sets: 203595_s_at (Human Genome U133 Plus 2.0 Array)   203596_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360860
NCBI entrez gene - 24138     See in Manteia.
OMIM - 616135
RefSeq - NM_012420
RefSeq Peptide - NP_036552
swissprot - Q13325
Ensembl - ENSG00000152778
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR759879.1ENSDARG00000088069Danio rerio
 ifit10ENSDARG00000007467Danio rerio
 ifit11ENSDARG00000090537Danio rerio
 ifit12ENSDARG00000090977Danio rerio
 ifit14ENSDARG00000071012Danio rerio
 ifit15ENSDARG00000043584Danio rerio
 ifit16ENSDARG00000056976Danio rerio
 ifit8ENSDARG00000057173Danio rerio
 IFIT5ENSGALG00000045085Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IFIT1 / P09914 / interferon induced protein with tetratricopeptide repeats 1ENSG0000018574555
IFIT1B / Q5T764 / interferon induced protein with tetratricopeptide repeats 1BENSG0000020401054
IFIT2 / P09913 / interferon induced protein with tetratricopeptide repeats 2ENSG0000011992244
IFIT3 / O14879 / interferon induced protein with tetratricopeptide repeats 3ENSG0000011991742


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013105  Tetratricopeptide repeat 2
 IPR019734  Tetratricopeptide repeat
 IPR024125  Interferon-induced protein with tetratricopeptide repeat 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008385 IkappaB kinase complex IMP
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045177 apical part of cell IDA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0000339 RNA cap binding IDA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008266 poly(U) RNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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