ENSG00000119917


Homo sapiens

Features
Gene ID: ENSG00000119917
  
Biological name :IFIT3
  
Synonyms : IFIT3 / interferon induced protein with tetratricopeptide repeats 3 / O14879
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.31
Gene start: 89327894
Gene end: 89340971
  
Corresponding Affymetrix probe sets: 204747_at (Human Genome U133 Plus 2.0 Array)   229450_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360876
Ensembl peptide - ENSP00000360883
NCBI entrez gene - 3437     See in Manteia.
OMIM - 604650
RefSeq - NM_001549
RefSeq - NM_001031683
RefSeq - NM_001289759
RefSeq Peptide - NP_001026853
RefSeq Peptide - NP_001276688
RefSeq Peptide - NP_001540
swissprot - O14879
swissprot - Q5T765
Ensembl - ENSG00000119917
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR759879.1ENSDARG00000088069Danio rerio
 ifit10ENSDARG00000007467Danio rerio
 ifit11ENSDARG00000090537Danio rerio
 ifit12ENSDARG00000090977Danio rerio
 ifit14ENSDARG00000071012Danio rerio
 ifit15ENSDARG00000043584Danio rerio
 ifit16ENSDARG00000056976Danio rerio
 ifit8ENSDARG00000057173Danio rerio
 IFIT5ENSGALG00000045085Gallus gallus
 Ifit3ENSMUSG00000074896Mus musculus
 Ifit3bENSMUSG00000062488Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IFIT2 / P09913 / interferon induced protein with tetratricopeptide repeats 2ENSG0000011992254
IFIT1B / Q5T764 / interferon induced protein with tetratricopeptide repeats 1BENSG0000020401043
IFIT5 / Q13325 / interferon induced protein with tetratricopeptide repeats 5ENSG0000015277841
IFIT1 / P09914 / interferon induced protein with tetratricopeptide repeats 1ENSG0000018574541


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR024122  Interferon-induced protein with tetratricopeptide repeats 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009615 response to virus IMP
 biological_processGO:0035457 cellular response to interferon-alpha IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IBA
 biological_processGO:0060337 type I interferon signaling pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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