ENSG00000119922


Homo sapiens

Features
Gene ID: ENSG00000119922
  
Biological name :IFIT2
  
Synonyms : IFIT2 / interferon induced protein with tetratricopeptide repeats 2 / P09913
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.31
Gene start: 89283694
Gene end: 89309276
  
Corresponding Affymetrix probe sets: 217502_at (Human Genome U133 Plus 2.0 Array)   226757_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484770
Ensembl peptide - ENSP00000490935
Ensembl peptide - ENSP00000360891
NCBI entrez gene - 3433     See in Manteia.
OMIM - 147040
RefSeq - NM_001547
RefSeq Peptide - NP_001538
swissprot - A0A087X279
swissprot - P09913
Ensembl - ENSG00000119922
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR759879.1ENSDARG00000088069Danio rerio
 ifit10ENSDARG00000007467Danio rerio
 ifit11ENSDARG00000090537Danio rerio
 ifit12ENSDARG00000090977Danio rerio
 ifit14ENSDARG00000071012Danio rerio
 ifit15ENSDARG00000043584Danio rerio
 ifit16ENSDARG00000056976Danio rerio
 ifit8ENSDARG00000057173Danio rerio
 IFIT5ENSGALG00000045085Gallus gallus
 Ifit2ENSMUSG00000045932Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IFIT3 / O14879 / interferon induced protein with tetratricopeptide repeats 3ENSG0000011991756
IFIT1 / P09914 / interferon induced protein with tetratricopeptide repeats 1ENSG0000018574545
IFIT5 / Q13325 / interferon induced protein with tetratricopeptide repeats 5ENSG0000015277845
IFIT1B / Q5T764 / interferon induced protein with tetratricopeptide repeats 1BENSG0000020401044


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR024124  Interferon-induced protein with tetratricopeptide repeats 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008637 apoptotic mitochondrial changes TAS
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0035457 cellular response to interferon-alpha IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IBA
 biological_processGO:0060337 type I interferon signaling pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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