ENSG00000153029


Homo sapiens

Features
Gene ID: ENSG00000153029
  
Biological name :MR1
  
Synonyms : major histocompatibility complex, class I-related / MR1 / Q95460
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q25.3
Gene start: 181033425
Gene end: 181061938
  
Corresponding Affymetrix probe sets: 207565_s_at (Human Genome U133 Plus 2.0 Array)   207566_at (Human Genome U133 Plus 2.0 Array)   210223_s_at (Human Genome U133 Plus 2.0 Array)   210224_at (Human Genome U133 Plus 2.0 Array)   210528_at (Human Genome U133 Plus 2.0 Array)   235352_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478976
Ensembl peptide - ENSP00000282990
Ensembl peptide - ENSP00000356551
Ensembl peptide - ENSP00000356552
Ensembl peptide - ENSP00000388504
Ensembl peptide - ENSP00000477563
NCBI entrez gene - 3140     See in Manteia.
OMIM - 600764
RefSeq - XM_011509463
RefSeq - NM_001194999
RefSeq - NM_001195000
RefSeq - NM_001195035
RefSeq - NM_001310213
RefSeq - NM_001531
RefSeq - XM_006711286
RefSeq Peptide - NP_001181964
RefSeq Peptide - NP_001297142
RefSeq Peptide - NP_001522
RefSeq Peptide - NP_001181928
RefSeq Peptide - NP_001181929
swissprot - Q95460
Ensembl - ENSG00000153029
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR339041.1ENSDARG00000051710Danio rerio
 CR339041.2ENSDARG00000051711Danio rerio
 CR339041.3ENSDARG00000115781Danio rerio
 FO904903.1ENSDARG00000059039Danio rerio
 mhc1laaENSDARG00000016056Danio rerio
 mhc1lbaENSDARG00000016227Danio rerio
 mhc1ldaENSDARG00000023203Danio rerio
 mhc1lfaENSDARG00000051712Danio rerio
 mhc1lgaENSDARG00000051713Danio rerio
 mhc1liaENSDARG00000097766Danio rerio
 mhc1ljaENSDARG00000096830Danio rerio
 mhc1llaENSDARG00000096977Danio rerio
 mhc1ubaENSDARG00000075963Danio rerio
 mhc1ukaENSDARG00000092731Danio rerio
 mhc1umaENSDARG00000039164Danio rerio
 si:ch211-147g22.4ENSDARG00000097275Danio rerio
 si:dkey-225f5.5ENSDARG00000055813Danio rerio
 si:dkey-52p2.5ENSDARG00000096940Danio rerio
 ENSGALG00000040901Gallus gallus
 ENSGALG00000043619Gallus gallus
 ENSGALG00000035251Gallus gallus
 ENSGALG00000032602Gallus gallus
 ENSGALG00000030320Gallus gallus
 ENSGALG00000026466Gallus gallus
 BF1ENSGALG00000033932Gallus gallus
 BF2ENSGALG00000041380Gallus gallus
 Mr1ENSMUSG00000026471Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HFE / Q30201 / hemochromatosisENSG0000001070432
AZGP1 / P25311 / alpha-2-glycoprotein 1, zinc-bindingENSG0000016086228
FCGRT / P55899 / Fc fragment of IgG receptor and transporterENSG0000010487027
MICA / MHC class I polypeptide-related sequence AENSG0000020452023
MICB / Q29980 / MHC class I polypeptide-related sequence BENSG0000020451623


Protein motifs (from Interpro)
Interpro ID Name
 IPR001039  MHC class I alpha chain, alpha1 alpha2 domains
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002367 cytokine production involved in immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002474 antigen processing and presentation of peptide antigen via MHC class I IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0032611 interleukin-1 beta production IEA
 biological_processGO:0032620 interleukin-17 production IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042612 MHC class I protein complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032393 MHC class I receptor activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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