ENSG00000204516


Homo sapiens

Features
Gene ID: ENSG00000204516
  
Biological name :MICB
  
Synonyms : MHC class I polypeptide-related sequence B / MICB / Q29980
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.33
Gene start: 31494881
Gene end: 31511124
  
Corresponding Affymetrix probe sets: 205905_s_at (Human Genome U133 Plus 2.0 Array)   206247_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252229
Ensembl peptide - ENSP00000382103
Ensembl peptide - ENSP00000442345
NCBI entrez gene - 4277     See in Manteia.
OMIM - 602436
RefSeq - NM_001289161
RefSeq - NM_001289160
RefSeq - NM_005931
RefSeq Peptide - NP_001276089
RefSeq Peptide - NP_001276090
RefSeq Peptide - NP_005922
swissprot - X6R344
swissprot - Q29980
swissprot - F5H7Q8
Ensembl - ENSG00000204516
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR339041.1ENSDARG00000051710Danio rerio
 CR339041.2ENSDARG00000051711Danio rerio
 CR339041.3ENSDARG00000115781Danio rerio
 FO904903.1ENSDARG00000059039Danio rerio
 mhc1laaENSDARG00000016056Danio rerio
 mhc1lbaENSDARG00000016227Danio rerio
 mhc1ldaENSDARG00000023203Danio rerio
 mhc1lfaENSDARG00000051712Danio rerio
 mhc1lgaENSDARG00000051713Danio rerio
 mhc1liaENSDARG00000097766Danio rerio
 mhc1ljaENSDARG00000096830Danio rerio
 mhc1llaENSDARG00000096977Danio rerio
 mhc1ubaENSDARG00000075963Danio rerio
 mhc1ukaENSDARG00000092731Danio rerio
 mhc1umaENSDARG00000039164Danio rerio
 si:ch211-147g22.4ENSDARG00000097275Danio rerio
 si:dkey-225f5.5ENSDARG00000055813Danio rerio
 si:dkey-52p2.5ENSDARG00000096940Danio rerio
 Mill1ENSMUSG00000054005Mus musculus
 Mill2ENSMUSG00000040987Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MICA / MHC class I polypeptide-related sequence AENSG0000020452071
HFE / Q30201 / hemochromatosisENSG0000001070424
MR1 / Q95460 / major histocompatibility complex, class I-relatedENSG0000015302921
AZGP1 / P25311 / alpha-2-glycoprotein 1, zinc-bindingENSG0000016086220
FCGRT / P55899 / Fc fragment of IgG receptor and transporterENSG0000010487020


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001913 T cell mediated cytotoxicity IBA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002429 immune response-activating cell surface receptor signaling pathway IDA
 biological_processGO:0006979 response to oxidative stress IDA
 biological_processGO:0009408 response to heat IDA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019835 cytolysis IEA
 biological_processGO:0032526 response to retinoic acid IDA
 biological_processGO:0042267 natural killer cell mediated cytotoxicity IBA
 biological_processGO:0046629 gamma-delta T cell activation IDA
 biological_processGO:0050689 negative regulation of defense response to virus by host IDA
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0046703 natural killer cell lectin-like receptor binding IDA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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