ENSMUSG00000040987


Mus musculus

Features
Gene ID: ENSMUSG00000040987
  
Biological name :Mill2
  
Synonyms : MHC I like leukocyte 2 / Mill2
  
Possible biological names infered from orthology : MHC class I polypeptide-related sequence A / MHC class I polypeptide-related sequence B / MICA / MICB / Q29980
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A3
Gene start: 18839966
Gene end: 18865402
  
Corresponding Affymetrix probe sets: 10550501 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000072246
Ensembl peptide - ENSMUSP00000154222
Ensembl peptide - ENSMUSP00000154268
Ensembl peptide - ENSMUSP00000072223
Ensembl peptide - ENSMUSP00000145895
NCBI entrez gene - 243864     See in Manteia.
MGI - MGI:2179989
RefSeq - XM_017322235
RefSeq - NM_153760
RefSeq - NM_153761
RefSeq - XM_006539932
RefSeq - XM_006539933
RefSeq - XM_006539934
RefSeq - XM_017322234
RefSeq Peptide - NP_715641
RefSeq Peptide - NP_715642
swissprot - A0A0U1RPA1
swissprot - Q8HWE5
swissprot - Q8HWE6
Ensembl - ENSMUSG00000040987
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR339041.1ENSDARG00000051710Danio rerio
 CR339041.2ENSDARG00000051711Danio rerio
 CR339041.3ENSDARG00000115781Danio rerio
 FO904903.1ENSDARG00000059039Danio rerio
 mhc1laaENSDARG00000016056Danio rerio
 mhc1lbaENSDARG00000016227Danio rerio
 mhc1ldaENSDARG00000023203Danio rerio
 mhc1lfaENSDARG00000051712Danio rerio
 mhc1lgaENSDARG00000051713Danio rerio
 mhc1liaENSDARG00000097766Danio rerio
 mhc1ljaENSDARG00000096830Danio rerio
 mhc1llaENSDARG00000096977Danio rerio
 mhc1ubaENSDARG00000075963Danio rerio
 mhc1ukaENSDARG00000092731Danio rerio
 mhc1umaENSDARG00000039164Danio rerio
 si:ch211-147g22.4ENSDARG00000097275Danio rerio
 si:dkey-225f5.5ENSDARG00000055813Danio rerio
 si:dkey-52p2.5ENSDARG00000096940Danio rerio
 MICAENSG00000204520Homo sapiens
 MICBENSG00000204516Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mill1 / MICA* / MICB* / Q29980* / MHC class I polypeptide-related sequence A* / MHC class I polypeptide-related sequence B*ENSMUSG0000005400560
Mr1 / Q8HWB0 / major histocompatibility complex, class I-related / Q95460*ENSMUSG0000002647126
Hfe / P70387 / Hereditary hemochromatosis protein homolog / Q30201* / hemochromatosis*ENSMUSG0000000661125
Azgp1 / Q64726 / Zinc-alpha-2-glycoprotein / P25311* / alpha-2-glycoprotein 1, zinc-binding*ENSMUSG0000003705321
Fcgrt / Q61559 / Mus musculus Fc receptor, IgG, alpha chain transporter (Fcgrt), transcript variant 2, mRNA. / P55899* / Fc fragment of IgG receptor and transporter*ENSMUSG0000000342021
H2-T24ENSMUSG0000005383521
H2-M10.1ENSMUSG0000002444821
H2-M10.6 / histocompatibility 2, M region locus 10.6ENSMUSG0000003713020
H2-M10.3ENSMUSG0000005812420
H2-M10.2 / histocompatibility 2, M region locus 10.2ENSMUSG0000002308319
H2-T10 / histocompatibility 2, T region locus 10ENSMUSG0000007949119
H2-M10.5ENSMUSG0000003724619
H2-T22 / histocompatibility 2, T region locus 22ENSMUSG0000005611619
H2-M10.4ENSMUSG0000004823118
2410137M14Rik / RIKEN cDNA 2410137M14 geneENSMUSG000000643086


Protein motifs (from Interpro)
Interpro ID Name
 IPR001039  MHC class I alpha chain, alpha1 alpha2 domains
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002429 immune response-activating cell surface receptor signaling pathway ISO
 biological_processGO:0006979 response to oxidative stress ISO
 biological_processGO:0009408 response to heat ISO
 biological_processGO:0032526 response to retinoic acid ISO
 biological_processGO:0046629 gamma-delta T cell activation ISO
 biological_processGO:0050689 negative regulation of defense response to virus by host ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046703 natural killer cell lectin-like receptor binding ISO


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030149 Klrk1 / O54709 / NKG2-D type II integral membrane protein / P26718* / killer cell lectin like receptor K1*  / complex / reaction
 ENSMUSG00000064109 Hcst / Q9QUJ0 / Hematopoietic cell signal transducer / Q9UBK5*  / reaction / complex






 

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