ENSG00000154133


Homo sapiens

Features
Gene ID: ENSG00000154133
  
Biological name :ROBO4
  
Synonyms : Q8WZ75 / ROBO4 / roundabout guidance receptor 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q24.2
Gene start: 124883691
Gene end: 124898500
  
Corresponding Affymetrix probe sets: 220758_s_at (Human Genome U133 Plus 2.0 Array)   226028_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437129
Ensembl peptide - ENSP00000304945
NCBI entrez gene - 54538     See in Manteia.
OMIM - 607528
RefSeq - XM_011542875
RefSeq - NM_001301088
RefSeq - NM_019055
RefSeq - XM_006718861
RefSeq Peptide - NP_061928
RefSeq Peptide - NP_001288017
swissprot - Q8WZ75
swissprot - B4DYV8
Ensembl - ENSG00000154133
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 robo4ENSDARG00000009387Danio rerio
 ENSGALG00000043088Gallus gallus
 Robo4ENSMUSG00000032125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ROBO1 / Q9Y6N7 / roundabout guidance receptor 1ENSG0000016985531
ROBO2 / Q9HCK4 / roundabout guidance receptor 2ENSG0000018500825
ROBO3 / Q96MS0 / roundabout guidance receptor 3ENSG0000015413425
CDON / Q4KMG0 / cell adhesion associated, oncogene regulatedENSG0000006430915
BOC / Q9BWV1 / BOC cell adhesion associated, oncogene regulatedENSG0000014485713
NCAM1 / P13591 / neural cell adhesion molecule 1ENSG000001492949
NCAM2 / O15394 / neural cell adhesion molecule 2ENSG000001546549


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IGI
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030334 regulation of cell migration NAS
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr