ENSG00000156127


Homo sapiens

Features
Gene ID: ENSG00000156127
  
Biological name :BATF
  
Synonyms : basic leucine zipper ATF-like transcription factor / BATF / Q16520
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 75522425
Gene end: 75547015
  
Corresponding Affymetrix probe sets: 205965_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286639
Ensembl peptide - ENSP00000450486
NCBI entrez gene - 10538     See in Manteia.
OMIM - 612476
RefSeq - NM_006399
RefSeq Peptide - NP_006390
swissprot - Q16520
swissprot - G3V266
Ensembl - ENSG00000156127
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 batfENSDARG00000011818Danio rerio
 BATFENSGALG00000010323Gallus gallus
 BatfENSMUSG00000034266Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BATF3 / Q9NR55 / basic leucine zipper ATF-like transcription factor 3ENSG0000012368543
BATF2 / Q8N1L9 / basic leucine zipper ATF-like transcription factor 2ENSG0000016806234


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR029820  Basic leucine zipper transcriptional factor ATF-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001816 cytokine production IEA
 biological_processGO:0002320 lymphoid progenitor cell differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030330 DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0042832 defense response to protozoan IEA
 biological_processGO:0043011 myeloid dendritic cell differentiation IEA
 biological_processGO:0045064 T-helper 2 cell differentiation IEA
 biological_processGO:0045190 isotype switching IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060218 hematopoietic stem cell differentiation IEA
 biological_processGO:0072539 T-helper 17 cell differentiation IEA
 biological_processGO:0072540 T-helper 17 cell lineage commitment IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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