ENSG00000156136


Homo sapiens

Features
Gene ID: ENSG00000156136
  
Biological name :DCK
  
Synonyms : DCK / deoxycytidine kinase / P27707
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q13.3
Gene start: 70992538
Gene end: 71030914
  
Corresponding Affymetrix probe sets: 203302_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286648
Ensembl peptide - ENSP00000426389
Ensembl peptide - ENSP00000425578
Ensembl peptide - ENSP00000422971
Ensembl peptide - ENSP00000421508
NCBI entrez gene - 1633     See in Manteia.
OMIM - 125450
RefSeq - NM_000788
RefSeq Peptide - NP_000779
swissprot - D6RCP9
swissprot - D6R9C6
swissprot - F5CTF3
swissprot - D6RG38
swissprot - P27707
swissprot - D6RFG8
Ensembl - ENSG00000156136
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dckENSDARG00000044807Danio rerio
 DCKENSGALG00000028501Gallus gallus
 DckENSMUSG00000029366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DGUOK / Q16854 / deoxyguanosine kinaseENSG0000011495647
TK2 / O00142 / thymidine kinase 2, mitochondrialENSG0000016654831


Protein motifs (from Interpro)
Interpro ID Name
 IPR002624  Deoxynucleoside kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031314  Deoxynucleoside kinase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006220 pyrimidine nucleotide metabolic process TAS
 biological_processGO:0009157 deoxyribonucleoside monophosphate biosynthetic process IEA
 biological_processGO:0009165 nucleotide biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043097 pyrimidine nucleoside salvage TAS
 biological_processGO:0043101 purine-containing compound salvage TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004137 deoxycytidine kinase activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019206 nucleoside kinase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Pyrimidine salvage
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000156136 DCK / P27707 / deoxycytidine kinase  / complex






 

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