ENSG00000158481


Homo sapiens

Features
Gene ID: ENSG00000158481
  
Biological name :CD1C
  
Synonyms : CD1C / CD1c molecule / P29017
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.1
Gene start: 158289786
Gene end: 158293630
  
Corresponding Affymetrix probe sets: 205987_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357152
Ensembl peptide - ENSP00000408755
NCBI entrez gene - 911     See in Manteia.
OMIM - 188340
RefSeq - XM_005245579
RefSeq - NM_001765
RefSeq Peptide - NP_001756
swissprot - P29017
swissprot - H0Y6Y6
Ensembl - ENSG00000158481
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD1BENSGALG00000043052Gallus gallus
 CD1CENSGALG00000030270Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD1B / P29016 / CD1b moleculeENSG0000015848560
CD1A / P06126 / CD1a moleculeENSG0000015847756
CD1E / P15812 / CD1e moleculeENSG0000015848853
CD1D / P15813 / CD1d moleculeENSG0000015847349


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002286 T cell activation involved in immune response IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib IBA
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0030881 beta-2-microglobulin binding IBA
 molecular_functionGO:0030883 endogenous lipid antigen binding IDA
 molecular_functionGO:0030884 exogenous lipid antigen binding IDA
 molecular_functionGO:0051861 glycolipid binding IDA
 molecular_functionGO:0071723 lipopeptide binding IDA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167286 CD3D / P04234 / CD3d molecule  / reaction / complex
 ENSG00000160654 CD3G / P09693 / CD3g molecule  / complex / reaction
 ENSG00000198821 CD247 / P20963 / CD247 molecule  / complex / reaction
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / complex
 ENSG00000198851 CD3E / P07766 / CD3e molecule  / complex / reaction
 ENSG00000211799 TRAV19 / T cell receptor alpha variable 19  / reaction / complex






 

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