ENSG00000158473


Homo sapiens

Features
Gene ID: ENSG00000158473
  
Biological name :CD1D
  
Synonyms : CD1D / CD1d molecule / P15813
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.1
Gene start: 158179947
Gene end: 158184896
  
Corresponding Affymetrix probe sets: 205789_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357153
NCBI entrez gene - 912     See in Manteia.
OMIM - 188410
RefSeq - XM_011510127
RefSeq - NM_001319145
RefSeq - NM_001766
RefSeq - XM_005245583
RefSeq - XM_006711621
RefSeq - XM_011510125
RefSeq Peptide - NP_001757
RefSeq Peptide - NP_001306074
swissprot - P15813
Ensembl - ENSG00000158473
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD1BENSGALG00000043052Gallus gallus
 CD1CENSGALG00000030270Gallus gallus
 Cd1d1ENSMUSG00000028076Mus musculus
 Cd1d2ENSMUSG00000041750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD1E / P15812 / CD1e moleculeENSG0000015848853
CD1B / P29016 / CD1b moleculeENSG0000015848552
CD1A / P06126 / CD1a moleculeENSG0000015847750
CD1C / P29017 / CD1c moleculeENSG0000015848149


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016045 detection of bacterium TAS
 biological_processGO:0034113 heterotypic cell-cell adhesion TAS
 biological_processGO:0042102 positive regulation of T cell proliferation IDA
 biological_processGO:0045058 T cell selection TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response TAS
 biological_processGO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib IDA
 biological_processGO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib IBA
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 molecular_functionGO:0030881 beta-2-microglobulin binding TAS
 molecular_functionGO:0030882 lipid antigen binding IDA
 molecular_functionGO:0030883 endogenous lipid antigen binding IBA
 molecular_functionGO:0030884 exogenous lipid antigen binding IDA
 molecular_functionGO:0042393 histone binding IPI
 molecular_functionGO:0050839 cell adhesion molecule binding IPI
 molecular_functionGO:0071723 lipopeptide binding IBA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167286 CD3D / P04234 / CD3d molecule  / reaction / complex
 ENSG00000160654 CD3G / P09693 / CD3g molecule  / complex / reaction
 ENSG00000198821 CD247 / P20963 / CD247 molecule  / complex / reaction
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / complex
 ENSG00000198851 CD3E / P07766 / CD3e molecule  / complex / reaction
 ENSG00000211799 TRAV19 / T cell receptor alpha variable 19  / reaction / complex






 

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