ENSG00000211799


Homo sapiens

Features
Gene ID: ENSG00000211799
  
Biological name :TRAV19
  
Synonyms : T cell receptor alpha variable 19 / TRAV19
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 22007512
Gene end: 22008181
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000452148
swissprot - A0A0A6YYK7
Ensembl - ENSG00000211799
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRAV14DV4ENSDARG00000115145Danio rerio
 Trav16ENSMUSG00000076855Mus musculus
 Trav16d-dv11ENSMUSG00000076796Mus musculus
 Trav16nENSMUSG00000076822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRAV14DV4 / T cell receptor alpha variable 14/delta variable 4ENSG0000021179256
TRAV38-1 / T cell receptor alpha variable 38-1ENSG0000021181651
TRAV38-2DV8 / T cell receptor alpha variable 38-2/delta variable 8ENSG0000021181748
TRDV1 / T cell receptor delta variable 1ENSG0000021180417


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002377 immunoglobulin production IBA
 biological_processGO:0006955 immune response IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Downstream TCR signaling
Phosphorylation of CD3 and TCR zeta chains
Translocation of ZAP-70 to Immunological synapse
Generation of second messenger molecules
PD-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000010610 CD4 / P01730 / CD4 molecule  / reaction / complex
 ENSG00000103653 CSK / P41240 / C-terminal Src kinase  / reaction
 ENSG00000115085 ZAP70 / P43403 / zeta chain of T cell receptor associated protein kinase 70  / complex / reaction
 ENSG00000158477 CD1A / P06126 / CD1a molecule  / complex / reaction
 ENSG00000153563 CD8A / P01732 / CD8a molecule  / complex
 ENSG00000167286 CD3D / P04234 / CD3d molecule  / reaction / complex
 ENSG00000160654 CD3G / P09693 / CD3g molecule  / reaction / complex
 ENSG00000182866 LCK / P06239 / LCK proto-oncogene, Src family tyrosine kinase  / reaction / complex
 ENSG00000111679 PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6  / reaction
 ENSG00000196735 P01909 / HLA-DQA1 / major histocompatibility complex, class II, DQ alpha 1  / reaction / complex
 ENSG00000172116 CD8B / P10966 / CD8b molecule  / complex
 ENSG00000198821 CD247 / P20963 / CD247 molecule  / reaction / complex
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / complex / reaction
 ENSG00000179295 PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11  / reaction
 ENSG00000198851 CD3E / P07766 / CD3e molecule  / reaction / complex
 ENSG00000134242 PTPN22 / Q9Y2R2 / protein tyrosine phosphatase, non-receptor type 22  / reaction
 ENSG00000204287 P01903 / HLA-DRA / major histocompatibility complex, class II, DR alpha  / reaction / complex
 ENSG00000158473 CD1D / P15813 / CD1d molecule  / complex / reaction
 ENSG00000158485 CD1B / P29016 / CD1b molecule  / reaction / complex
 ENSG00000237541 P01906 / HLA-DQA2 / major histocompatibility complex, class II, DQ alpha 2  / reaction / complex
 ENSG00000213658 LAT / O43561 / linker for activation of T cells  / reaction
 ENSG00000158481 CD1C / P29017 / CD1c molecule  / reaction / complex
 ENSG00000231389 P20036 / HLA-DPA1 / major histocompatibility complex, class II, DP alpha 1  / complex / reaction
 ENSG00000124181 PLCG1 / P19174 / phospholipase C gamma 1  / reaction
 ENSG00000043462 LCP2 / Q13094 / lymphocyte cytosolic protein 2  / reaction
 ENSG00000100351 GRAP2 / O75791 / GRB2-related adaptor protein 2  / reaction
 ENSG00000211799 TRAV19 / T cell receptor alpha variable 19  / reaction
 ENSG00000065675 PRKCQ / Q04759 / protein kinase C theta  / reaction
 ENSG00000149177 PTPRJ / Q12913 / protein tyrosine phosphatase, receptor type J  / reaction






 

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