ENSG00000158806


Homo sapiens

Features
Gene ID: ENSG00000158806
  
Biological name :NPM2
  
Synonyms : NPM2 / nucleophosmin/nucleoplasmin 2 / Q86SE8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.3
Gene start: 22024125
Gene end: 22036897
  
Corresponding Affymetrix probe sets: 230977_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429984
Ensembl peptide - ENSP00000429413
Ensembl peptide - ENSP00000481018
Ensembl peptide - ENSP00000481077
Ensembl peptide - ENSP00000289820
Ensembl peptide - ENSP00000370941
Ensembl peptide - ENSP00000381032
Ensembl peptide - ENSP00000427741
Ensembl peptide - ENSP00000428016
NCBI entrez gene - 10361     See in Manteia.
OMIM - 608073
RefSeq - XM_017012950
RefSeq - XM_011544362
RefSeq - XM_011544363
RefSeq - XM_011544364
RefSeq - XM_017012947
RefSeq - XM_017012948
RefSeq - XM_017012949
RefSeq - NM_001286680
RefSeq - NM_001286681
RefSeq - NM_182795
RefSeq - XM_011544360
RefSeq Peptide - NP_877724
RefSeq Peptide - NP_001273609
RefSeq Peptide - NP_001273610
swissprot - E5RGN1
swissprot - Q86SE8
swissprot - E5RFQ8
Ensembl - ENSG00000158806
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 npm2bENSDARG00000053963Danio rerio
 Npm2ENSMUSG00000047911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPM1 / P06748 / nucleophosmin 1ENSG0000018116333
NPM3 / O75607 / nucleophosmin/nucleoplasmin 3ENSG0000010783325


Protein motifs (from Interpro)
Interpro ID Name
 IPR004301  Nucleoplasmin family
 IPR024057  Nucleoplasmin core domain
 IPR036824  Nucleoplasmin core domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001824 blastocyst development IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IDA
 biological_processGO:0007096 regulation of exit from mitosis IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007338 single fertilization IMP
 biological_processGO:0009994 oocyte differentiation IEP
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0045836 positive regulation of meiotic nuclear division IMP
 biological_processGO:0051054 positive regulation of DNA metabolic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 cellular_componentGO:0000789 cytoplasmic chromatin IDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042393 histone binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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