ENSMUSG00000047911


Mus musculus

Features
Gene ID: ENSMUSG00000047911
  
Biological name :Npm2
  
Synonyms : Npm2 / Nucleoplasmin-2 / Q80W85
  
Possible biological names infered from orthology : nucleophosmin/nucleoplasmin 2 / Q86SE8
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D2
Gene start: 70647302
Gene end: 70659244
  
Corresponding Affymetrix probe sets: 10421444 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000057365
Ensembl peptide - ENSMUSP00000154427
NCBI entrez gene - 328440     See in Manteia.
MGI - MGI:1890811
RefSeq - XM_017316061
RefSeq - NM_181345
RefSeq - XM_006519147
RefSeq - XM_011245091
RefSeq - XM_006519143
RefSeq - XM_006519145
RefSeq - XM_006519146
RefSeq Peptide - NP_851990
swissprot - Q80W85
Ensembl - ENSMUSG00000047911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 npm2bENSDARG00000053963Danio rerio
 NPM2ENSG00000158806Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Npm1 / Q61937 / nucleophosmin 1ENSMUSG0000005711333
Npm3 / Q9CPP0 / Nucleoplasmin-3 / O75607* / nucleophosmin/nucleoplasmin 3*ENSMUSG0000005620923


Protein motifs (from Interpro)
Interpro ID Name
 IPR004301  Nucleoplasmin family
 IPR024057  Nucleoplasmin core domain
 IPR036824  Nucleoplasmin core domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001824 blastocyst development IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0007096 regulation of exit from mitosis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007338 single fertilization ISS
 biological_processGO:0009994 oocyte differentiation IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0045836 positive regulation of meiotic nuclear division IEA
 biological_processGO:0051054 positive regulation of DNA metabolic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 cellular_componentGO:0000789 cytoplasmic chromatin IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001125 abnormal oocytes "anomalous structure of immature ova" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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