ENSG00000159055


Homo sapiens

Features
Gene ID: ENSG00000159055
  
Biological name :MIS18A
  
Synonyms : MIS18A / MIS18 kinetochore protein A / Q9NYP9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.11
Gene start: 32268219
Gene end: 32279069
  
Corresponding Affymetrix probe sets: 219004_s_at (Human Genome U133 Plus 2.0 Array)   228597_at (Human Genome U133 Plus 2.0 Array)   229671_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290130
NCBI entrez gene - 54069     See in Manteia.
RefSeq - NM_018944
RefSeq Peptide - NP_061817
swissprot - Q9NYP9
Ensembl - ENSG00000159055
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mis18aENSDARG00000035333Danio rerio
 MIS18AENSGALG00000015884Gallus gallus
 Mis18aENSMUSG00000022978Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004910  Yippee/Mis18/Cereblon
 IPR034752  Mis18 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0034080 CENP-A containing nucleosome assembly IEA
 biological_processGO:0044030 regulation of DNA methylation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0000775 chromosome, centromeric region IBA
 cellular_componentGO:0000785 chromatin IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deposition of new CENPA-containing nucleosomes at the centromere


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104147 OIP5 / O43482 / Opa interacting protein 5  / complex
 ENSG00000115163 CENPA / P49450 / centromere protein A  / complex
 ENSG00000129534 Q6P0N0 / MIS18BP1 / MIS18 binding protein 1  / complex
 ENSG00000137812 KNL1 / Q8NG31 / kinetochore scaffold 1  / reaction / complex
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / complex






 

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