ENSG00000159388


Homo sapiens

Features
Gene ID: ENSG00000159388
  
Biological name :BTG2
  
Synonyms : BTG2 / BTG anti-proliferation factor 2 / P78543
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 203305491
Gene end: 203309602
  
Corresponding Affymetrix probe sets: 201235_s_at (Human Genome U133 Plus 2.0 Array)   201236_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433553
Ensembl peptide - ENSP00000290551
NCBI entrez gene - 7832     See in Manteia.
OMIM - 601597
RefSeq - NM_006763
RefSeq Peptide - NP_006754
swissprot - P78543
Ensembl - ENSG00000159388
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 btg2ENSDARG00000020298Danio rerio
 BTG2ENSGALG00000026858Gallus gallus
 Btg2ENSMUSG00000020423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BTG1 / P62324 / BTG anti-proliferation factor 1ENSG0000013363966
TOB1 / P50616 / transducer of ERBB2, 1ENSG0000014123239
TOB2 / Q14106 / transducer of ERBB2, 2ENSG0000018386437
BTG3 / Q14201 / BTG anti-proliferation factor 3ENSG0000015464032
BTG4 / Q9NY30 / BTG anti-proliferation factor 4ENSG0000013770730


Protein motifs (from Interpro)
Interpro ID Name
 IPR002087  Anti-proliferative protein
 IPR033328  Protein BTG2
 IPR036054  BTG-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0010243 response to organonitrogen compound IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0017148 negative regulation of translation IDA
 biological_processGO:0021542 dentate gyrus development IEA
 biological_processGO:0021954 central nervous system neuron development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0031175 neuron projection development IMP
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IDA
 biological_processGO:2000178 negative regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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