ENSG00000183864


Homo sapiens

Features
Gene ID: ENSG00000183864
  
Biological name :TOB2
  
Synonyms : Q14106 / TOB2 / transducer of ERBB2, 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.2
Gene start: 41433492
Gene end: 41447023
  
Corresponding Affymetrix probe sets: 221496_s_at (Human Genome U133 Plus 2.0 Array)   222243_s_at (Human Genome U133 Plus 2.0 Array)   234720_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388549
Ensembl peptide - ENSP00000331305
NCBI entrez gene - 10766     See in Manteia.
OMIM - 607396
RefSeq - XM_017028539
RefSeq - NM_016272
RefSeq - XM_005261315
RefSeq - XM_006724105
RefSeq Peptide - NP_057356
swissprot - B0QXZ4
swissprot - Q14106
Ensembl - ENSG00000183864
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TOB2ENSGALG00000011957Gallus gallus
 Tob2ENSMUSG00000048546Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TOB1 / P50616 / transducer of ERBB2, 1ENSG0000014123259
BTG1 / P62324 / BTG anti-proliferation factor 1ENSG0000013363919
BTG2 / P78543 / BTG anti-proliferation factor 2ENSG0000015938817
BTG3 / Q14201 / BTG anti-proliferation factor 3ENSG0000015464016
BTG4 / Q9NY30 / BTG anti-proliferation factor 4ENSG0000013770713


Protein motifs (from Interpro)
Interpro ID Name
 IPR002087  Anti-proliferative protein
 IPR009818  Ataxin-2, C-terminal
 IPR015676  Tob1/2
 IPR015678  Tob2
 IPR036054  BTG-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007292 female gamete generation TAS
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0023052 signaling IBA
 biological_processGO:0045671 negative regulation of osteoclast differentiation IEA
 biological_processGO:0045778 positive regulation of ossification IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042809 vitamin D receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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