ENSG00000160209


Homo sapiens

Features
Gene ID: ENSG00000160209
  
Biological name :PDXK
  
Synonyms : O00764 / PDXK / pyridoxal kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.3
Gene start: 43719094
Gene end: 43762307
  
Corresponding Affymetrix probe sets: 1566670_at (Human Genome U133 Plus 2.0 Array)   1566671_a_at (Human Genome U133 Plus 2.0 Array)   202671_s_at (Human Genome U133 Plus 2.0 Array)   218018_at (Human Genome U133 Plus 2.0 Array)   218019_s_at (Human Genome U133 Plus 2.0 Array)   222492_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381155
Ensembl peptide - ENSP00000291565
Ensembl peptide - ENSP00000333624
Ensembl peptide - ENSP00000418359
Ensembl peptide - ENSP00000479315
Ensembl peptide - ENSP00000420708
NCBI entrez gene - 8566     See in Manteia.
NCBI entrez gene - 105372824     See in Manteia.
OMIM - 179020
RefSeq - XM_017028484
RefSeq - XM_005261196
RefSeq - XM_005261198
RefSeq - XM_005261199
RefSeq - XM_011529758
RefSeq - XM_011529760
RefSeq - XM_011529761
RefSeq - XM_011529811
RefSeq - XM_017028483
RefSeq - NM_001331030
RefSeq - NM_003681
RefSeq - XM_005261195
RefSeq Peptide - NP_003672
RefSeq Peptide - NP_001317959
swissprot - F2Z2Y4
swissprot - V9HWC3
swissprot - A0A0B4J2C9
swissprot - A8MV33
swissprot - O00764
swissprot - A8MT14
Ensembl - ENSG00000160209
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdxkaENSDARG00000088959Danio rerio
 pdxkbENSDARG00000036546Danio rerio
 PDXKENSGALG00000016205Gallus gallus
 PdxkENSMUSG00000032788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004625  Pyridoxine kinase
 IPR013749  Pyridoxamine kinase/Phosphomethylpyrimidine kinase
 IPR029056  Ribokinase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0009443 pyridoxal 5"-phosphate salvage IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042816 vitamin B6 metabolic process TAS
 biological_processGO:0042823 pyridoxal phosphate biosynthetic process IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0008478 pyridoxal kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IDA
 molecular_functionGO:0030955 potassium ion binding IDA
 molecular_functionGO:0031402 sodium ion binding IDA
 molecular_functionGO:0031403 lithium ion binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Vitamins B6 activation to pyridoxal phosphate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000160209 PDXK / O00764 / pyridoxal kinase  / complex






 

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