ENSMUSG00000032788


Mus musculus

Features
Gene ID: ENSMUSG00000032788
  
Biological name :Pdxk
  
Synonyms : Pdxk / Pyridoxal kinase / Q8K183
  
Possible biological names infered from orthology : O00764
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 78436744
Gene end: 78464975
  
Corresponding Affymetrix probe sets: 10370497 (MoGene1.0st)   1427929_a_at (Mouse Genome 430 2.0 Array)   1427930_at (Mouse Genome 430 2.0 Array)   1427931_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038540
NCBI entrez gene - 216134     See in Manteia.
MGI - MGI:1351869
RefSeq - NM_172134
RefSeq Peptide - NP_742146
swissprot - Q8K183
Ensembl - ENSMUSG00000032788
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdxkaENSDARG00000088959Danio rerio
 pdxkbENSDARG00000036546Danio rerio
 PDXKENSGALG00000016205Gallus gallus
 PDXKENSG00000160209Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004625  Pyridoxine kinase
 IPR013749  Pyridoxamine kinase/Phosphomethylpyrimidine kinase
 IPR029056  Ribokinase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009443 pyridoxal 5"-phosphate salvage IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042823 pyridoxal phosphate biosynthetic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008478 pyridoxal kinase activity ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0030955 potassium ion binding IEA
 molecular_functionGO:0031402 sodium ion binding IEA
 molecular_functionGO:0031403 lithium ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Vitamins B6 activation to pyridoxal phosphate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pcsk5tm1b(KOMP)Mbp/Pcsk5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Pcsk5tm1b(KOMP)Mbp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032788 Pdxk / Q8K183 / Pyridoxal kinase / O00764*  / complex






 

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