ENSG00000160447


Homo sapiens

Features
Gene ID: ENSG00000160447
  
Biological name :PKN3
  
Synonyms : PKN3 / protein kinase N3 / Q6P5Z2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 128702523
Gene end: 128720918
  
Corresponding Affymetrix probe sets: 226299_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000291906
NCBI entrez gene - 29941     See in Manteia.
OMIM - 610714
RefSeq - XM_017014650
RefSeq - NM_001317926
RefSeq - NM_013355
RefSeq - XM_005251946
RefSeq - XM_006717080
RefSeq - XM_017014649
RefSeq Peptide - NP_001304855
RefSeq Peptide - NP_037487
swissprot - A0A024R8D6
swissprot - Q6P5Z2
Ensembl - ENSG00000160447
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pkn3ENSDARG00000079585Danio rerio
 PKN3ENSGALG00000004689Gallus gallus
 Pkn3ENSMUSG00000026785Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PKN1 / Q16512 / protein kinase N1ENSG0000012314353
PKN2 / Q16513 / protein kinase N2ENSG0000006524352
AL355916.3ENSG000002589897


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011072  HR1 rho-binding domain
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR035892  C2 domain superfamily
 IPR036274  HR1 repeat superfamily
 IPR037313  Serine/threonine-protein kinase N, first HR1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0010631 epithelial cell migration IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004697 protein kinase C activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017049 GTP-Rho binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate PKNs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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