ENSG00000160883


Homo sapiens

Features
Gene ID: ENSG00000160883
  
Biological name :HK3
  
Synonyms : hexokinase 3 / HK3 / P52790
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q35.2
Gene start: 176880869
Gene end: 176899332
  
Corresponding Affymetrix probe sets: 205936_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427000
Ensembl peptide - ENSP00000292432
Ensembl peptide - ENSP00000422169
Ensembl peptide - ENSP00000424632
NCBI entrez gene - 3101     See in Manteia.
OMIM - 142570
RefSeq - XM_017009411
RefSeq - NM_002115
RefSeq - XM_011534540
RefSeq Peptide - NP_002106
swissprot - H0YAG4
swissprot - A0A024R7R1
swissprot - P52790
swissprot - H0Y8U9
swissprot - H0Y9N6
Ensembl - ENSG00000160883
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000036895Gallus gallus
 ENSGALG00000027287Gallus gallus
 Hk3ENSMUSG00000025877Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HK2 / P52789 / hexokinase 2ENSG0000015939955
HK1 / P19367 / hexokinase 1ENSG0000015651552
HKDC1 / Q2TB90 / hexokinase domain containing 1ENSG0000015651052
GCK / P35557 / glucokinaseENSG0000010663321


Protein motifs (from Interpro)
Interpro ID Name
 IPR001312  Hexokinase
 IPR019807  Hexokinase, binding site
 IPR022672  Hexokinase, N-terminal
 IPR022673  Hexokinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001678 cellular glucose homeostasis IEA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019318 hexose metabolic process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 biological_processGO:0051156 glucose 6-phosphate metabolic process IEA
 biological_processGO:0061621 canonical glycolysis TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004340 glucokinase activity TAS
 molecular_functionGO:0004396 hexokinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005536 glucose binding IEA
 molecular_functionGO:0008865 fructokinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016773 phosphotransferase activity, alcohol group as acceptor IEA
 molecular_functionGO:0019158 mannokinase activity IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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