ENSG00000156510


Homo sapiens

Features
Gene ID: ENSG00000156510
  
Biological name :HKDC1
  
Synonyms : hexokinase domain containing 1 / HKDC1 / Q2TB90
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.1
Gene start: 69220303
Gene end: 69267559
  
Corresponding Affymetrix probe sets: 220585_at (Human Genome U133 Plus 2.0 Array)   227614_at (Human Genome U133 Plus 2.0 Array)   237323_at (Human Genome U133 Plus 2.0 Array)   237324_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000346643
NCBI entrez gene - 80201     See in Manteia.
OMIM - 617221
RefSeq - NM_025130
RefSeq - XM_011540195
RefSeq Peptide - NP_079406
swissprot - Q2TB90
Ensembl - ENSG00000156510
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hkdc1ENSDARG00000038703Danio rerio
 HKDC1ENSGALG00000021039Gallus gallus
 Hkdc1ENSMUSG00000020080Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HK1 / P19367 / hexokinase 1ENSG0000015651570
HK2 / P52789 / hexokinase 2ENSG0000015939968
HK3 / P52790 / hexokinase 3ENSG0000016088352
GCK / P35557 / glucokinaseENSG0000010663324


Protein motifs (from Interpro)
Interpro ID Name
 IPR001312  Hexokinase
 IPR019807  Hexokinase, binding site
 IPR022672  Hexokinase, N-terminal
 IPR022673  Hexokinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001678 cellular glucose homeostasis IBA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006096 glycolytic process IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019318 hexose metabolic process IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 biological_processGO:0051156 glucose 6-phosphate metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004340 glucokinase activity IBA
 molecular_functionGO:0004396 hexokinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005536 glucose binding IEA
 molecular_functionGO:0008865 fructokinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016773 phosphotransferase activity, alcohol group as acceptor IEA
 molecular_functionGO:0019158 mannokinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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