ENSG00000161016


Homo sapiens

Features
Gene ID: ENSG00000161016
  
Biological name :RPL8
  
Synonyms : P62917 / ribosomal protein L8 / RPL8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 144789765
Gene end: 144792587
  
Corresponding Affymetrix probe sets: 200936_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433703
Ensembl peptide - ENSP00000434535
Ensembl peptide - ENSP00000437062
Ensembl peptide - ENSP00000436460
Ensembl peptide - ENSP00000435313
Ensembl peptide - ENSP00000262584
Ensembl peptide - ENSP00000378378
Ensembl peptide - ENSP00000433464
NCBI entrez gene - 6132     See in Manteia.
OMIM - 604177
RefSeq - XM_017013723
RefSeq - NM_000973
RefSeq - NM_001317771
RefSeq - NM_001317782
RefSeq - NM_033301
RefSeq Peptide - NP_001304711
RefSeq Peptide - NP_150644
RefSeq Peptide - NP_000964
RefSeq Peptide - NP_001304700
swissprot - G3V1A1
swissprot - H0YF23
swissprot - E9PKZ0
swissprot - E9PKU4
swissprot - P62917
swissprot - E9PP36
Ensembl - ENSG00000161016
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl8ENSDARG00000014867Danio rerio
 RPL8ENSGALG00000016232Gallus gallus
 Rpl8ENSMUSG00000003970Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002171  Ribosomal protein L2
 IPR008991  Translation protein SH3-like domain superfamily
 IPR012340  Nucleic acid-binding, OB-fold
 IPR014722  Ribosomal protein L2, domain 2
 IPR014726  Ribosomal protein L2, domain 3
 IPR022666  Ribosomal Proteins L2, RNA binding domain
 IPR022669  Ribosomal protein L2, C-terminal
 IPR022671  Ribosomal protein L2, conserved site
 IPR023672  Ribosomal protein L2, archaeal-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015934 large ribosomal subunit IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit TAS
 cellular_componentGO:0042788 polysomal ribosome IDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0019843 rRNA binding IEA
 molecular_functionGO:1990932 5.8S rRNA binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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