ENSG00000161542


Homo sapiens

Features
Gene ID: ENSG00000161542
  
Biological name :PRPSAP1
  
Synonyms : phosphoribosyl pyrophosphate synthetase associated protein 1 / PRPSAP1 / Q14558
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 76309486
Gene end: 76384521
  
Corresponding Affymetrix probe sets: 1556715_at (Human Genome U133 Plus 2.0 Array)   202529_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000314973
Ensembl peptide - ENSP00000414624
Ensembl peptide - ENSP00000409190
Ensembl peptide - ENSP00000402126
Ensembl peptide - ENSP00000392838
Ensembl peptide - ENSP00000387494
NCBI entrez gene - 5635     See in Manteia.
OMIM - 601249
RefSeq - XM_011525034
RefSeq - NM_002766
RefSeq Peptide - NP_001317432
RefSeq Peptide - NP_002757
swissprot - C9JNQ3
swissprot - C9JUN4
swissprot - Q14558
swissprot - C9J168
swissprot - C9JKT9
swissprot - B4DP31
Ensembl - ENSG00000161542
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prpsap1ENSDARG00000099222Danio rerio
 PRPSAP1ENSGALG00000021539Gallus gallus
 Prpsap1ENSMUSG00000015869Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60256 / PRPSAP2 / phosphoribosyl pyrophosphate synthetase associated protein 2ENSG0000014112772
P21108 / PRPS1L1 / phosphoribosyl pyrophosphate synthetase 1-like 1ENSG0000022993737
PRPS1 / P60891 / phosphoribosyl pyrophosphate synthetase 1ENSG0000014722437
PRPS2 / P11908 / phosphoribosyl pyrophosphate synthetase 2ENSG0000010191137


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR005946  Ribose-phosphate pyrophosphokinase
 IPR029057  Phosphoribosyltransferase-like
 IPR029099  Ribose-phosphate pyrophosphokinase, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process TAS
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0009165 nucleotide biosynthetic process IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004749 ribose phosphate diphosphokinase activity IEA
 molecular_functionGO:0004857 enzyme inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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