ENSG00000229937


Homo sapiens

Features
Gene ID: ENSG00000229937
  
Biological name :PRPS1L1
  
Synonyms : P21108 / phosphoribosyl pyrophosphate synthetase 1-like 1 / PRPS1L1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p21.1
Gene start: 18026774
Gene end: 18027863
  
Corresponding Affymetrix probe sets: 215486_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424595
Ensembl peptide - ENSP00000492583
NCBI entrez gene - 221823     See in Manteia.
OMIM - 611566
RefSeq - NM_175886
RefSeq Peptide - NP_787082
swissprot - A0A0B4J207
swissprot - P21108
Ensembl - ENSG00000229937
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prps1aENSDARG00000015524Danio rerio
 prps1bENSDARG00000037506Danio rerio
 ENSGALG00000004908Gallus gallus
 Prps1ENSMUSG00000031432Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRPS1 / P60891 / phosphoribosyl pyrophosphate synthetase 1ENSG0000014722494
PRPS2 / P11908 / phosphoribosyl pyrophosphate synthetase 2ENSG0000010191190
O60256 / PRPSAP2 / phosphoribosyl pyrophosphate synthetase associated protein 2ENSG0000014112747
Q14558 / PRPSAP1 / phosphoribosyl pyrophosphate synthetase associated protein 1ENSG0000016154245


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR000842  Phosphoribosyl pyrophosphate synthetase, conserved site
 IPR005946  Ribose-phosphate pyrophosphokinase
 IPR029057  Phosphoribosyltransferase-like
 IPR029099  Ribose-phosphate pyrophosphokinase, N-terminal domain
 IPR037515  Ribose-phosphate pyrophosphokinase, bacterial-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006015 5-phosphoribose 1-diphosphate biosynthetic process IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0009156 ribonucleoside monophosphate biosynthetic process IEA
 biological_processGO:0009165 nucleotide biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0044249 cellular biosynthetic process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004749 ribose phosphate diphosphokinase activity NAS
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
5-Phosphoribose 1-diphosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000229937 P21108 / PRPS1L1 / phosphoribosyl pyrophosphate synthetase 1-like 1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr