ENSG00000161955


Homo sapiens

Features
Gene ID: ENSG00000161955
  
Biological name :TNFSF13
  
Synonyms : O75888 / TNFSF13 / TNF superfamily member 13
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.1
Gene start: 7558292
Gene end: 7561608
  
Corresponding Affymetrix probe sets: 209499_x_at (Human Genome U133 Plus 2.0 Array)   209500_x_at (Human Genome U133 Plus 2.0 Array)   210314_x_at (Human Genome U133 Plus 2.0 Array)   211495_x_at (Human Genome U133 Plus 2.0 Array)   229326_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410094
Ensembl peptide - ENSP00000390771
Ensembl peptide - ENSP00000464998
Ensembl peptide - ENSP00000486052
Ensembl peptide - ENSP00000314455
Ensembl peptide - ENSP00000343505
Ensembl peptide - ENSP00000369908
Ensembl peptide - ENSP00000379792
Ensembl peptide - ENSP00000379794
NCBI entrez gene - 8741     See in Manteia.
OMIM - 604472
RefSeq - NM_001198622
RefSeq - NM_001198623
RefSeq - NM_001198624
RefSeq - NM_003808
RefSeq - NM_172087
RefSeq - NM_172088
RefSeq Peptide - NP_742084
RefSeq Peptide - NP_001185551
RefSeq Peptide - NP_001185552
RefSeq Peptide - NP_001185553
RefSeq Peptide - NP_003799
RefSeq Peptide - NP_742085
swissprot - O75888
swissprot - Q2QBA2
swissprot - C9JFN2
swissprot - K7EJ28
swissprot - C9JF68
Ensembl - ENSG00000161955
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnfsf13ENSDARG00000091556Danio rerio
 Tnfsf13ENSMUSG00000089669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNFSF12-TNFSF13 / TNFSF12-TNFSF13 readthroughENSG0000024887158
Q9Y275 / TNFSF13B / TNF superfamily member 13bENSG0000010252424
O43508 / TNFSF12 / TNF superfamily member 12ENSG0000023969713


Protein motifs (from Interpro)
Interpro ID Name
 IPR006052  Tumour necrosis factor domain
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR021184  Tumour necrosis factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0043488 regulation of mRNA stability TAS
 biological_processGO:0048298 positive regulation of isotype switching to IgA isotypes IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
HuR (ELAVL1) binds and stabilizes mRNA
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000048462 Q02223 / TNFRSF17 / TNF receptor superfamily member 17  / complex / reaction
 ENSG00000240505 O14836 / TNFRSF13B / TNF receptor superfamily member 13B  / reaction / complex
 ENSG00000161955 O75888 / TNFSF13 / TNF superfamily member 13  / complex






 

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