ENSG00000163376


Homo sapiens

Features
Gene ID: ENSG00000163376
  
Biological name :KBTBD8
  
Synonyms : KBTBD8 / kelch repeat and BTB domain containing 8 / Q8NFY9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p14.1
Gene start: 66998307
Gene end: 67011210
  
Corresponding Affymetrix probe sets: 239835_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417341
Ensembl peptide - ENSP00000419738
Ensembl peptide - ENSP00000418075
Ensembl peptide - ENSP00000401878
NCBI entrez gene - 84541     See in Manteia.
OMIM - 616607
RefSeq - NM_032505
RefSeq - XM_005264771
RefSeq Peptide - NP_115894
swissprot - C9JAA6
swissprot - C9J331
swissprot - Q8NFY9
Ensembl - ENSG00000163376
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kbtbd8ENSDARG00000070698Danio rerio
 KBTBD8ENSGALG00000007569Gallus gallus
 Kbtbd8ENSMUSG00000030031Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KBTBD2 / Q8IY47 / kelch repeat and BTB domain containing 2ENSG0000017085233
KBTBD6 / Q86V97 / kelch repeat and BTB domain containing 6ENSG0000016557227
KBTBD7 / Q8WVZ9 / kelch repeat and BTB domain containing 7ENSG0000012069627
KLHL40 / Q2TBA0 / kelch like family member 40ENSG0000015711925
KLHL24 / Q6TFL4 / kelch like family member 24ENSG0000011479625
KLHL6 / Q8WZ60 / kelch like family member 6ENSG0000017257824
Q3ZCT8 / KBTBD12 / kelch repeat and BTB domain containing 12ENSG0000018771524
KLHL41 / O60662 / kelch like family member 41ENSG0000023947423
KLHL29 / Q96CT2 / kelch like family member 29ENSG0000011977122
KLHL25 / Q9H0H3 / kelch like family member 25ENSG0000018365522
KLHL23 / Q8NBE8 / kelch like family member 23ENSG0000021316022
ENC1 / O14682 / ectodermal-neural cortex 1ENSG0000017161722
KLHL35 / Q6PF15 / kelch like family member 35ENSG0000014924321
KLHL38 / Q2WGJ6 / kelch like family member 38ENSG0000017594621
KLHL30 / Q0D2K2 / kelch like family member 30ENSG0000016842720
KLHL21 / Q9UJP4 / kelch like family member 21ENSG0000016241320
KBTBD3 / Q8NAB2 / kelch repeat and BTB domain containing 3ENSG0000018235919


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR028764  Kelch repeat and BTB domain-containing protein 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006513 protein monoubiquitination IDA
 biological_processGO:0014029 neural crest formation IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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