ENSG00000172578


Homo sapiens

Features
Gene ID: ENSG00000172578
  
Biological name :KLHL6
  
Synonyms : kelch like family member 6 / KLHL6 / Q8WZ60
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q27.1
Gene start: 183487531
Gene end: 183555689
  
Corresponding Affymetrix probe sets: 1555275_a_at (Human Genome U133 Plus 2.0 Array)   1560396_at (Human Genome U133 Plus 2.0 Array)   1560397_s_at (Human Genome U133 Plus 2.0 Array)   228167_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000341342
Ensembl peptide - ENSP00000433734
NCBI entrez gene - 89857     See in Manteia.
OMIM - 614214
RefSeq - NM_130446
RefSeq - XM_011513273
RefSeq Peptide - NP_569713
swissprot - A0A0C4DGF2
swissprot - Q8WZ60
Ensembl - ENSG00000172578
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl6ENSDARG00000026990Danio rerio
 KLHL6ENSGALG00000002263Gallus gallus
 Klhl6ENSMUSG00000043008Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL24 / Q6TFL4 / kelch like family member 24ENSG0000011479642
KLHL35 / Q6PF15 / kelch like family member 35ENSG0000014924334
ENC1 / O14682 / ectodermal-neural cortex 1ENSG0000017161727
KLHL25 / Q9H0H3 / kelch like family member 25ENSG0000018365527
KLHL29 / Q96CT2 / kelch like family member 29ENSG0000011977127
KLHL21 / Q9UJP4 / kelch like family member 21ENSG0000016241326
KLHL38 / Q2WGJ6 / kelch like family member 38ENSG0000017594626
KLHL23 / Q8NBE8 / kelch like family member 23ENSG0000021316025
KBTBD8 / Q8NFY9 / kelch repeat and BTB domain containing 8ENSG0000016337624
KLHL30 / Q0D2K2 / kelch like family member 30ENSG0000016842724
KLHL40 / Q2TBA0 / kelch like family member 40ENSG0000015711923
Q3ZCT8 / KBTBD12 / kelch repeat and BTB domain containing 12ENSG0000018771522
KBTBD6 / Q86V97 / kelch repeat and BTB domain containing 6ENSG0000016557222
KBTBD7 / Q8WVZ9 / kelch repeat and BTB domain containing 7ENSG0000012069622
KBTBD2 / Q8IY47 / kelch repeat and BTB domain containing 2ENSG0000017085221
KLHL41 / O60662 / kelch like family member 41ENSG0000023947421
KBTBD3 / Q8NAB2 / kelch repeat and BTB domain containing 3ENSG0000018235921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR029851  Kelch-like protein 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002467 germinal center formation IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0050853 B cell receptor signaling pathway IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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