ENSG00000162413


Homo sapiens

Features
Gene ID: ENSG00000162413
  
Biological name :KLHL21
  
Synonyms : kelch like family member 21 / KLHL21 / Q9UJP4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.31
Gene start: 6590724
Gene end: 6614607
  
Corresponding Affymetrix probe sets: 203068_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468710
Ensembl peptide - ENSP00000366891
Ensembl peptide - ENSP00000366886
Ensembl peptide - ENSP00000466089
Ensembl peptide - ENSP00000480631
Ensembl peptide - ENSP00000466479
NCBI entrez gene - 9903     See in Manteia.
OMIM - 616262
RefSeq - NM_001324309
RefSeq - NM_014851
RefSeq Peptide - NP_001311238
RefSeq Peptide - NP_055666
swissprot - Q9UJP4
swissprot - K7ELI0
swissprot - K7EMF2
swissprot - K7ESH2
swissprot - Q2NKK7
Ensembl - ENSG00000162413
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl21ENSDARG00000039255Danio rerio
 KLHL21ENSGALG00000035211Gallus gallus
 Klhl21ENSMUSG00000073700Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLHL30 / Q0D2K2 / kelch like family member 30ENSG0000016842736
KLHL29 / Q96CT2 / kelch like family member 29ENSG0000011977131
ENC1 / O14682 / ectodermal-neural cortex 1ENSG0000017161729
KLHL24 / Q6TFL4 / kelch like family member 24ENSG0000011479629
KLHL25 / Q9H0H3 / kelch like family member 25ENSG0000018365529
KLHL38 / Q2WGJ6 / kelch like family member 38ENSG0000017594628
KLHL35 / Q6PF15 / kelch like family member 35ENSG0000014924328
KLHL6 / Q8WZ60 / kelch like family member 6ENSG0000017257827
KLHL23 / Q8NBE8 / kelch like family member 23ENSG0000021316027
KBTBD6 / Q86V97 / kelch repeat and BTB domain containing 6ENSG0000016557225
KBTBD7 / Q8WVZ9 / kelch repeat and BTB domain containing 7ENSG0000012069625
KLHL40 / Q2TBA0 / kelch like family member 40ENSG0000015711924
KBTBD2 / Q8IY47 / kelch repeat and BTB domain containing 2ENSG0000017085222
KLHL41 / O60662 / kelch like family member 41ENSG0000023947422
Q3ZCT8 / KBTBD12 / kelch repeat and BTB domain containing 12ENSG0000018771522
KBTBD3 / Q8NAB2 / kelch repeat and BTB domain containing 3ENSG0000018235921
KBTBD8 / Q8NFY9 / kelch repeat and BTB domain containing 8ENSG0000016337620


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032465 regulation of cytokinesis IMP
 biological_processGO:0035853 chromosome passenger complex localization to spindle midzone IMP
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005827 polar microtubule IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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