ENSDARG00000039255


Danio rerio

Features
Gene ID: ENSDARG00000039255
  
Biological name :klhl21
  
Synonyms : kelch-like family member 21 / klhl21 / Q6NYM1
  
Possible biological names infered from orthology : Kelch-like protein 21 / Q3U410 / Q9UJP4
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 24926407
Gene end: 24939148
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000121765
Ensembl peptide - ENSDARP00000115156
Ensembl peptide - ENSDARP00000119274
NCBI entrez gene - 404613     See in Manteia.
RefSeq - NM_001320407
RefSeq - XM_005162160
RefSeq Peptide - NP_001307336
swissprot - Q6NYM1
swissprot - E9QFL2
ZFIN ID - ZDB-GENE-040426-2627
Ensembl - ENSDARG00000039255
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL21ENSGALG00000035211Gallus gallus
 KLHL21ENSG00000162413Homo sapiens
 Klhl21ENSMUSG00000073700Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
klhl30 / kelch-like family member 30 / Q0D2K2* / Q8C3F7* / Kelch-like protein 30 *ENSDARG0000007609431
klhl24b / kelch-like family member 24b / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000000827530
klhl24a / kelch-like family member 24a / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000002173930
enc2 / ectodermal-neural cortex 2 / KLHL25* / Q9H0H3* / kelch like family member 25*ENSDARG0000010241829
zmp:0000000619 / KLHL29* / Q96CT2* / kelch like family member 29*ENSDARG0000004379929
klhl29 / kelch-like family member 29 / Q96CT2*ENSDARG0000008768829
enc1 / ectodermal-neural cortex 1 / O14682* / O35709* / Ectoderm-neural cortex protein 1 *ENSDARG0000003539828
enc3 / ectodermal-neural cortex 3ENSDARG0000005832228
si:ch211-256e16.3ENSDARG0000005242628
klhl23 / kelch-like family member 23 / Q6GQU2* / Q8NBE8* / Kelch-like protein 23 *ENSDARG0000007847527
klhl38b / kelch-like family member 38b / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000004027827
Q1LYM6 / klhl38a / kelch-like family member 38a / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000003138327
klhl6 / kelch-like family member 6 / Q6V595* / Q8WZ60* / Kelch-like protein 6 *ENSDARG0000002699025
kbtbd8 / kelch repeat and BTB (POZ) domain containing 8 / Q8NFY9* / Q3UQV5* / kelch repeat and BTB domain containing 8* / Kelch repeat and BTB domain-containing protein 8 *ENSDARG0000007069824
klhl35 / kelch-like family member 35 / Q6PF15* / Q9CZ49* / Kelch-like protein 35 *ENSDARG0000006357724
Q3ZB90 / kbtbd12 / kelch repeat and BTB (POZ) domain containing 12 / Q3ZCT8* / Q9D618* / kelch repeat and BTB domain containing 12* / Kelch repeat and BTB domain-containing protein 12 *ENSDARG0000000188224
kbtbd2 / kelch repeat and BTB (POZ) domain containing 2 / Q8IY47* / kelch repeat and BTB domain containing 2*ENSDARG0000008722622
E9QJ30 / klhl40b / kelch-like family member 40b / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000001912522
kbtbd7 / kelch repeat and BTB (POZ) domain containing 7 / Q86V97* / KBTBD6* / Q8WVZ9* / uncharacterized protein LOC432879 * / kelch repeat and BTB domain containing 7* / kelch repeat and BT...ENSDARG0000007800122
B3DIV9 / klhl40a / kelch-like family member 40a / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000003905222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination ISS
 biological_processGO:0032465 regulation of cytokinesis ISS
 biological_processGO:0035853 chromosome passenger complex localization to spindle midzone ISS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005827 polar microtubule ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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