ENSDARG00000078001


Danio rerio

Features
Gene ID: ENSDARG00000078001
  
Biological name :kbtbd7
  
Synonyms : kbtbd7 / kelch repeat and BTB (POZ) domain containing 7
  
Possible biological names infered from orthology : KBTBD6 / kelch repeat and BTB domain containing 6 / kelch repeat and BTB domain containing 7 / Q86V97 / Q8WVZ9 / uncharacterized protein LOC432879
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 17423941
Gene end: 17425881
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000103717
Ensembl peptide - ENSDARP00000128961
NCBI entrez gene - 794299     See in Manteia.
swissprot - A8WHU9
swissprot - X1WFF7
ZFIN ID - ZDB-GENE-070912-204
Ensembl - ENSDARG00000078001
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KBTBD6ENSG00000165572Homo sapiens
 KBTBD7ENSG00000120696Homo sapiens
 Kbtbd6ENSMUSG00000075502Mus musculus
 Kbtbd7ENSMUSG00000043881Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kbtbd8 / kelch repeat and BTB (POZ) domain containing 8 / Q8NFY9* / Q3UQV5* / kelch repeat and BTB domain containing 8* / Kelch repeat and BTB domain-containing protein 8 *ENSDARG0000007069825
klhl21 / Q6NYM1 / kelch-like family member 21 / Q3U410* / Q9UJP4* / Kelch-like protein 21 *ENSDARG0000003925522
Q3ZB90 / kbtbd12 / kelch repeat and BTB (POZ) domain containing 12 / Q3ZCT8* / Q9D618* / kelch repeat and BTB domain containing 12* / Kelch repeat and BTB domain-containing protein 12 *ENSDARG0000000188222
kbtbd2 / kelch repeat and BTB (POZ) domain containing 2 / Q8IY47* / kelch repeat and BTB domain containing 2*ENSDARG0000008722622
si:ch211-256e16.3ENSDARG0000005242621
klhl6 / kelch-like family member 6 / Q6V595* / Q8WZ60* / Kelch-like protein 6 *ENSDARG0000002699021
klhl24a / kelch-like family member 24a / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000002173920
enc2 / ectodermal-neural cortex 2 / KLHL25* / Q9H0H3* / kelch like family member 25*ENSDARG0000010241820
enc1 / ectodermal-neural cortex 1 / O14682* / O35709* / Ectoderm-neural cortex protein 1 *ENSDARG0000003539820
E9QJ30 / klhl40b / kelch-like family member 40b / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000001912520
enc3 / ectodermal-neural cortex 3ENSDARG0000005832220
B3DIV9 / klhl40a / kelch-like family member 40a / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000003905219
zmp:0000000619 / KLHL29* / Q96CT2* / kelch like family member 29*ENSDARG0000004379919
klhl29 / kelch-like family member 29 / Q96CT2*ENSDARG0000008768819
klhl24b / kelch-like family member 24b / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000000827519
klhl30 / kelch-like family member 30 / Q0D2K2* / Q8C3F7* / Kelch-like protein 30 *ENSDARG0000007609419
klhl38b / kelch-like family member 38b / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000004027818
Q1LYM6 / klhl38a / kelch-like family member 38a / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000003138318
klhl23 / kelch-like family member 23 / Q6GQU2* / Q8NBE8* / Kelch-like protein 23 *ENSDARG0000007847518
kbtbd3 / kelch repeat and BTB (POZ) domain containing 3 / Q8NAB2* / Q8BHI4* / kelch repeat and BTB domain containing 3* / Kelch repeat and BTB domain-containing protein 3 *ENSDARG0000006051217


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038967 cul3a / cullin 3a / CUL3* / Q13618* / Q9JLV5* / cullin 3*  / complex
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSDARG00000100108 cul3b / cullin 3b / CUL3* / Q13618* / Q9JLV5* / cullin 3*  / complex






 

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