ENSDARG00000019125


Danio rerio

Features
Gene ID: ENSDARG00000019125
  
Biological name :klhl40b
  
Synonyms : E9QJ30 / kelch-like family member 40b / klhl40b
  
Possible biological names infered from orthology : kelch like family member 40 / KLHL40 / Q2TBA0
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 20575259
Gene end: 20581672
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000012991
NCBI entrez gene - 795319     See in Manteia.
swissprot - E9QJ30
ZFIN ID - ZDB-GENE-060227-1
Ensembl - ENSDARG00000019125
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL40ENSGALG00000005292Gallus gallus
 KLHL40ENSG00000157119Homo sapiens
 Klhl40ENSMUSG00000074001Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B3DIV9 / klhl40a / kelch-like family member 40a / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000003905263
F1QEG2 / klhl41b / kelch-like family member 41b / KLHL41* / O60662* / kelch like family member 41*ENSDARG0000000675750
E9QIN8 / klhl41a / kelch-like family member 41a / O60662* / KLHL41* / A2AUC9* / Kelch-like protein 41 * / kelch like family member 41*ENSDARG0000006888847
klhl24a / kelch-like family member 24a / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000002173925
klhl38b / kelch-like family member 38b / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000004027825
kbtbd8 / kelch repeat and BTB (POZ) domain containing 8 / Q8NFY9* / Q3UQV5* / kelch repeat and BTB domain containing 8* / Kelch repeat and BTB domain-containing protein 8 *ENSDARG0000007069825
enc3 / ectodermal-neural cortex 3ENSDARG0000005832224
si:ch211-256e16.3ENSDARG0000005242624
Q1LYM6 / klhl38a / kelch-like family member 38a / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000003138324
enc2 / ectodermal-neural cortex 2 / KLHL25* / Q9H0H3* / kelch like family member 25*ENSDARG0000010241824
klhl24b / kelch-like family member 24b / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000000827524
Q3ZB90 / kbtbd12 / kelch repeat and BTB (POZ) domain containing 12 / Q3ZCT8* / Q9D618* / kelch repeat and BTB domain containing 12* / Kelch repeat and BTB domain-containing protein 12 *ENSDARG0000000188224
enc1 / ectodermal-neural cortex 1 / O14682* / O35709* / Ectoderm-neural cortex protein 1 *ENSDARG0000003539824
kbtbd2 / kelch repeat and BTB (POZ) domain containing 2 / Q8IY47* / kelch repeat and BTB domain containing 2*ENSDARG0000008722623
klhl6 / kelch-like family member 6 / Q6V595* / Q8WZ60* / Kelch-like protein 6 *ENSDARG0000002699022
klhl30 / kelch-like family member 30 / Q0D2K2* / Q8C3F7* / Kelch-like protein 30 *ENSDARG0000007609422
klhl21 / Q6NYM1 / kelch-like family member 21 / Q3U410* / Q9UJP4* / Kelch-like protein 21 *ENSDARG0000003925522
klhl35 / kelch-like family member 35 / Q6PF15* / Q9CZ49* / Kelch-like protein 35 *ENSDARG0000006357721
kbtbd7 / kelch repeat and BTB (POZ) domain containing 7 / Q86V97* / KBTBD6* / Q8WVZ9* / uncharacterized protein LOC432879 * / kelch repeat and BTB domain containing 7* / kelch repeat and BT...ENSDARG0000007800120
zmp:0000000619 / KLHL29* / Q96CT2* / kelch like family member 29*ENSDARG0000004379920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination ISS
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0036268 swimming IGI
 biological_processGO:0048741 skeletal muscle fiber development IEA
 biological_processGO:0061061 muscle structure development IMP
 biological_processGO:0098528 skeletal muscle fiber differentiation ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISS
 cellular_componentGO:0031672 A band IEA
 cellular_componentGO:0031674 I band IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism refractivity , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001117 post-vent region post-vent region morphology , abnormal
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 ZFA:0005277 skeletal muscle skeletal muscle myofibril undulate , abnormal
skeletal muscle myofibril loose , abnormal
skeletal muscle myofibril disorganized , abnormal
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 ZFA:0009115 skeletal muscle cell skeletal muscle cell Z disc increased width , abnormal
skeletal muscle cell Z disc disorganized , abnormal
skeletal muscle cell Z disc aggregated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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