ENSDARG00000006757


Danio rerio

Features
Gene ID: ENSDARG00000006757
  
Biological name :klhl41b
  
Synonyms : F1QEG2 / kelch-like family member 41b / klhl41b
  
Possible biological names infered from orthology : A2AUC9 / kelch like family member 41 / Kelch-like protein 41 / KLHL41 / O60662
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 3680651
Gene end: 3692280
  
Corresponding Affymetrix probe sets: Dr.3984.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000012238
swissprot - F1QEG2
ZFIN ID - ZDB-GENE-030131-9875
Ensembl - ENSDARG00000006757
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL41ENSGALG00000038813Gallus gallus
 KLHL41ENSG00000239474Homo sapiens
 A2AUC9ENSMUSG00000075307Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E9QIN8 / klhl41a / kelch-like family member 41a / O60662* / KLHL41* / A2AUC9* / Kelch-like protein 41 * / kelch like family member 41*ENSDARG0000006888872
B3DIV9 / klhl40a / kelch-like family member 40a / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000003905252
E9QJ30 / klhl40b / kelch-like family member 40b / KLHL40* / Q2TBA0* / kelch like family member 40*ENSDARG0000001912551
kbtbd2 / kelch repeat and BTB (POZ) domain containing 2 / Q8IY47* / kelch repeat and BTB domain containing 2*ENSDARG0000008722623
si:ch211-256e16.3ENSDARG0000005242623
Q3ZB90 / kbtbd12 / kelch repeat and BTB (POZ) domain containing 12 / Q3ZCT8* / Q9D618* / kelch repeat and BTB domain containing 12* / Kelch repeat and BTB domain-containing protein 12 *ENSDARG0000000188223
klhl24b / kelch-like family member 24b / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000000827523
enc2 / ectodermal-neural cortex 2 / KLHL25* / Q9H0H3* / kelch like family member 25*ENSDARG0000010241822
kbtbd8 / kelch repeat and BTB (POZ) domain containing 8 / Q8NFY9* / Q3UQV5* / kelch repeat and BTB domain containing 8* / Kelch repeat and BTB domain-containing protein 8 *ENSDARG0000007069822
klhl6 / kelch-like family member 6 / Q6V595* / Q8WZ60* / Kelch-like protein 6 *ENSDARG0000002699022
klhl24a / kelch-like family member 24a / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*ENSDARG0000002173922
klhl38b / kelch-like family member 38b / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000004027821
klhl30 / kelch-like family member 30 / Q0D2K2* / Q8C3F7* / Kelch-like protein 30 *ENSDARG0000007609421
Q1LYM6 / klhl38a / kelch-like family member 38a / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*ENSDARG0000003138321
klhl21 / Q6NYM1 / kelch-like family member 21 / Q3U410* / Q9UJP4* / Kelch-like protein 21 *ENSDARG0000003925520
enc3 / ectodermal-neural cortex 3ENSDARG0000005832220
enc1 / ectodermal-neural cortex 1 / O14682* / O35709* / Ectoderm-neural cortex protein 1 *ENSDARG0000003539820
zmp:0000000619 / KLHL29* / Q96CT2* / kelch like family member 29*ENSDARG0000004379919
klhl35 / kelch-like family member 35 / Q6PF15* / Q9CZ49* / Kelch-like protein 35 *ENSDARG0000006357719
klhl29 / kelch-like family member 29 / Q96CT2*ENSDARG0000008768819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030571  Kelch-like protein 41


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045214 sarcomere organization IEA
 biological_processGO:0045661 regulation of myoblast differentiation IBA
 biological_processGO:0048741 skeletal muscle fiber development IEA
 biological_processGO:2000291 regulation of myoblast proliferation IBA
 biological_processGO:2001014 regulation of skeletal muscle cell differentiation IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005856 cytoskeleton IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IEA
 cellular_componentGO:0031430 M band IBA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 cellular_componentGO:0033017 sarcoplasmic reticulum membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0005277 skeletal muscle skeletal muscle decreased size , abnormal
skeletal muscle refractivity , abnormal
skeletal muscle myofibril disorganized , abnormal
skeletal muscle sarcomere disorganized , abnormal
skeletal muscle Z disc increased thickness , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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