Manteia

ENSDARG00000068888

Danio rerio

Features

Gene ID:	ENSDARG00000068888

Biological name :	klhl41a

Synonyms :	E9QIN8 / kelch-like family member 41a / klhl41a

Possible biological names infered from orthology :	A2AUC9 / kelch like family member 41 / Kelch-like protein 41 / KLHL41 / O60662

Species:	Danio rerio

Chr. number:	9
Strand:	-1
Band:
Gene start:	48270379
Gene end:	48281941

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000090560 NCBI entrez gene - 100148315 See in Manteia. swissprot - E9QIN8 ZFIN ID - ZDB-GENE-081105-22 Ensembl - ENSDARG00000068888

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
KLHL41	ENSGALG00000038813	Gallus gallus
KLHL41	ENSG00000239474	Homo sapiens
A2AUC9	ENSMUSG00000075307	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
F1QEG2 / klhl41b / kelch-like family member 41b / KLHL41* / O60662* / kelch like family member 41*	ENSDARG00000006757	72
E9QJ30 / klhl40b / kelch-like family member 40b / KLHL40* / Q2TBA0* / kelch like family member 40*	ENSDARG00000019125	49
B3DIV9 / klhl40a / kelch-like family member 40a / KLHL40* / Q2TBA0* / kelch like family member 40*	ENSDARG00000039052	48
si:ch211-256e16.3	ENSDARG00000052426	24
Q3ZB90 / kbtbd12 / kelch repeat and BTB (POZ) domain containing 12 / Q3ZCT8* / Q9D618* / kelch repeat and BTB domain containing 12* / Kelch repeat and BTB domain-containing protein 12 *	ENSDARG00000001882	23
klhl6 / kelch-like family member 6 / Q6V595* / Q8WZ60* / Kelch-like protein 6 *	ENSDARG00000026990	22
klhl24b / kelch-like family member 24b / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*	ENSDARG00000008275	22
kbtbd8 / kelch repeat and BTB (POZ) domain containing 8 / Q8NFY9* / Q3UQV5* / kelch repeat and BTB domain containing 8* / Kelch repeat and BTB domain-containing protein 8 *	ENSDARG00000070698	22
enc2 / ectodermal-neural cortex 2 / KLHL25* / Q9H0H3* / kelch like family member 25*	ENSDARG00000102418	21
Q1LYM6 / klhl38a / kelch-like family member 38a / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*	ENSDARG00000031383	21
klhl38b / kelch-like family member 38b / Q8BSF5* / KLHL38* / Q2WGJ6* / Kelch-like protein 38 * / kelch like family member 38*	ENSDARG00000040278	21
klhl24a / kelch-like family member 24a / Q8BRG6* / KLHL24* / Q6TFL4* / Kelch-like protein 24 * / kelch like family member 24*	ENSDARG00000021739	21
kbtbd2 / kelch repeat and BTB (POZ) domain containing 2 / Q8IY47* / kelch repeat and BTB domain containing 2*	ENSDARG00000087226	20
klhl30 / kelch-like family member 30 / Q0D2K2* / Q8C3F7* / Kelch-like protein 30 *	ENSDARG00000076094	20
klhl21 / Q6NYM1 / kelch-like family member 21 / Q3U410* / Q9UJP4* / Kelch-like protein 21 *	ENSDARG00000039255	20
enc3 / ectodermal-neural cortex 3	ENSDARG00000058322	19
enc1 / ectodermal-neural cortex 1 / O14682* / O35709* / Ectoderm-neural cortex protein 1 *	ENSDARG00000035398	19
klhl29 / kelch-like family member 29 / Q96CT2*	ENSDARG00000087688	19
zmp:0000000619 / KLHL29* / Q96CT2* / kelch like family member 29*	ENSDARG00000043799	19
klhl23 / kelch-like family member 23 / Q6GQU2* / Q8NBE8* / Kelch-like protein 23 *	ENSDARG00000078475	18

Protein motifs (from Interpro)

Interpro ID	Name
IPR000210	BTB/POZ domain
IPR006652	Kelch repeat type 1
IPR011333	SKP1/BTB/POZ domain superfamily
IPR011705	BTB/Kelch-associated
IPR015915	Kelch-type beta propeller
IPR017096	BTB-kelch protein
IPR030571	Kelch-like protein 41

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0016567	protein ubiquitination	IEA
biological_process	GO:0035914	skeletal muscle cell differentiation	IEA
biological_process	GO:0045214	sarcomere organization	IEA
biological_process	GO:0045661	regulation of myoblast differentiation	IBA
biological_process	GO:0048741	skeletal muscle fiber development	IEA
biological_process	GO:2000291	regulation of myoblast proliferation	IBA
biological_process	GO:2001014	regulation of skeletal muscle cell differentiation	IBA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IEA
cellular_component	GO:0005789	endoplasmic reticulum membrane	IEA
cellular_component	GO:0005856	cytoskeleton	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016529	sarcoplasmic reticulum	IEA
cellular_component	GO:0031430	M band	IBA
cellular_component	GO:0031463	Cul3-RING ubiquitin ligase complex	IBA
cellular_component	GO:0033017	sarcoplasmic reticulum membrane	IEA
molecular_function	GO:0004842	ubiquitin-protein transferase activity	IBA

Pathways (from Reactome)

Pathway description

Neddylation

Antigen processing: Ubiquitination & Proteasome degradation

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000054	pericardium	pericardium edematous , abnormal	Show
ZFA:0000107	eye	eye decreased size , abnormal	Show
ZFA:0001094	whole organism	whole organism decreased size , abnormal whole organism dead , abnormal whole organism decreased thickness , abnormal	Show
ZFA:0001115	trunk	trunk curved , abnormal	Show
ZFA:0005277	skeletal muscle	skeletal muscle decreased size , abnormal skeletal muscle myofibril disorganized , abnormal skeletal muscle sarcomere absent , abnormal skeletal muscle sarcomere disorganized , abnormal skeletal muscle refractivity , abnormal skeletal muscle Z disc increased thickness , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr