ENSG00000183655


Homo sapiens

Features
Gene ID: ENSG00000183655
  
Biological name :KLHL25
  
Synonyms : kelch like family member 25 / KLHL25 / Q9H0H3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q25.3
Gene start: 85759323
Gene end: 85795030
  
Corresponding Affymetrix probe sets: 210307_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336800
NCBI entrez gene - 64410     See in Manteia.
RefSeq - NM_022480
RefSeq Peptide - NP_071925
swissprot - Q9H0H3
Ensembl - ENSG00000183655
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enc2ENSDARG00000102418Danio rerio
 KLHL25ENSGALG00000006826Gallus gallus
 Klhl25ENSMUSG00000055652Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENC1 / O14682 / ectodermal-neural cortex 1ENSG0000017161775
KLHL24 / Q6TFL4 / kelch like family member 24ENSG0000011479632
KLHL38 / Q2WGJ6 / kelch like family member 38ENSG0000017594630
KLHL21 / Q9UJP4 / kelch like family member 21ENSG0000016241330
KLHL35 / Q6PF15 / kelch like family member 35ENSG0000014924329
KLHL30 / Q0D2K2 / kelch like family member 30ENSG0000016842729
KLHL6 / Q8WZ60 / kelch like family member 6ENSG0000017257829
KLHL29 / Q96CT2 / kelch like family member 29ENSG0000011977128
KLHL23 / Q8NBE8 / kelch like family member 23ENSG0000021316027
KLHL40 / Q2TBA0 / kelch like family member 40ENSG0000015711925
KLHL41 / O60662 / kelch like family member 41ENSG0000023947424
Q3ZCT8 / KBTBD12 / kelch repeat and BTB domain containing 12ENSG0000018771523
KBTBD8 / Q8NFY9 / kelch repeat and BTB domain containing 8ENSG0000016337623
KBTBD3 / Q8NAB2 / kelch repeat and BTB domain containing 3ENSG0000018235923
KBTBD2 / Q8IY47 / kelch repeat and BTB domain containing 2ENSG0000017085222
KBTBD7 / Q8WVZ9 / kelch repeat and BTB domain containing 7ENSG0000012069621
KBTBD6 / Q86V97 / kelch repeat and BTB domain containing 6ENSG0000016557220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030565  Kelch-like protein 25
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006446 regulation of translational initiation IDA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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