ENSMUSG00000055652


Mus musculus

Features
Gene ID: ENSMUSG00000055652
  
Biological name :Klhl25
  
Synonyms : Kelch-like protein 25 / Klhl25 / Q8R2P1
  
Possible biological names infered from orthology : kelch like family member 25 / Q9H0H3
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: D1
Gene start: 75848310
Gene end: 75874131
  
Corresponding Affymetrix probe sets: 10554198 (MoGene1.0st)   1425192_at (Mouse Genome 430 2.0 Array)   1453101_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146102
Ensembl peptide - ENSMUSP00000146192
Ensembl peptide - ENSMUSP00000089707
Ensembl peptide - ENSMUSP00000133175
Ensembl peptide - ENSMUSP00000145600
NCBI entrez gene - 207952     See in Manteia.
MGI - MGI:2668031
RefSeq - NM_182782
RefSeq - XM_011250832
RefSeq - NM_001122780
RefSeq - NM_029652
RefSeq Peptide - NP_001116252
RefSeq Peptide - NP_083928
RefSeq Peptide - NP_877583
swissprot - A0A0U1RNK3
swissprot - A0A0U1RQ03
swissprot - Q8R2P1
Ensembl - ENSMUSG00000055652
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enc2ENSDARG00000102418Danio rerio
 KLHL25ENSGALG00000006826Gallus gallus
 KLHL25ENSG00000183655Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Enc1 / O35709 / Ectoderm-neural cortex protein 1 / O14682* / ectodermal-neural cortex 1*ENSMUSG0000004177373
Klhl24 / Q8BRG6 / Kelch-like protein 24 / Q6TFL4* / kelch like family member 24*ENSMUSG0000006290131
Klhl38 / Q8BSF5 / Kelch-like protein 38 / Q2WGJ6* / kelch like family member 38*ENSMUSG0000002235730
Klhl6 / Q6V595 / Kelch-like protein 6 / Q8WZ60* / kelch like family member 6*ENSMUSG0000004300829
Klhl21 / Q3U410 / Kelch-like protein 21 / Q9UJP4* / kelch like family member 21*ENSMUSG0000007370029
Klhl35 / Q9CZ49 / Kelch-like protein 35 / Q6PF15* / kelch like family member 35*ENSMUSG0000003529828
Klhl29 / Q80T74 / Kelch-like protein 29 / Q96CT2* / kelch like family member 29*ENSMUSG0000002062728
Klhl30 / Q8C3F7 / Kelch-like protein 30 / Q0D2K2* / kelch like family member 30*ENSMUSG0000002630828
Klhl23 / Q6GQU2 / Kelch-like protein 23 / Q8NBE8* / kelch like family member 23*ENSMUSG0000004215527
Klhl40 / kelch like family member 40 / Q2TBA0*ENSMUSG0000007400124
A2AUC9 / Klhl41 / Kelch-like protein 41 / O60662* / kelch like family member 41*ENSMUSG0000007530724
Kbtbd3 / Q8BHI4 / Kelch repeat and BTB domain-containing protein 3 / Q8NAB2* / kelch repeat and BTB domain containing 3*ENSMUSG0000002589324
Kbtbd8 / Q3UQV5 / Kelch repeat and BTB domain-containing protein 8 / Q8NFY9* / kelch repeat and BTB domain containing 8*ENSMUSG0000003003122
Q9D618 / Kbtbd12 / Kelch repeat and BTB domain-containing protein 12 / Q3ZCT8* / kelch repeat and BTB domain containing 12*ENSMUSG0000003318222
Kbtbd2 / kelch repeat and BTB domain containing 2 / Q8IY47*ENSMUSG0000005948622
Kbtbd7 / Q86V97* / Q8WVZ9* / KBTBD6* / kelch repeat and BTB domain containing 6* / kelch repeat and BTB domain containing 7*ENSMUSG0000004388121
Kbtbd6 / uncharacterized protein LOC432879 / Q86V97* / Q8WVZ9* / KBTBD7* / kelch repeat and BTB domain containing 6* / kelch repeat and BTB domain containing 7*ENSMUSG0000007550215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030565  Kelch-like protein 25
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006446 regulation of translational initiation ISS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0016567 protein ubiquitination ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISO
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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