ENSG00000164219


Homo sapiens

Features
Gene ID: ENSG00000164219
  
Biological name :PGGT1B
  
Synonyms : P53609 / PGGT1B / protein geranylgeranyltransferase type I subunit beta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q22.3
Gene start: 115204012
Gene end: 115262872
  
Corresponding Affymetrix probe sets: 206288_at (Human Genome U133 Plus 2.0 Array)   214202_at (Human Genome U133 Plus 2.0 Array)   235615_at (Human Genome U133 Plus 2.0 Array)   242844_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368935
Ensembl peptide - ENSP00000404676
NCBI entrez gene - 5229     See in Manteia.
OMIM - 602031
RefSeq - XM_011543492
RefSeq - NM_005023
RefSeq - XM_005272020
RefSeq - XM_011543490
RefSeq Peptide - NP_005014
swissprot - P53609
Ensembl - ENSG00000164219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pggt1bENSDARG00000103464Danio rerio
 PGGT1BENSGALG00000008197Gallus gallus
 Pggt1bENSMUSG00000024477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P53611 / RABGGTB / Rab geranylgeranyltransferase beta subunitENSG0000013795525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001330  PFTB repeat
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0018344 protein geranylgeranylation TAS
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0051771 negative regulation of nitric-oxide synthase biosynthetic process IEA
 cellular_componentGO:0005953 CAAX-protein geranylgeranyltransferase complex TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004659 prenyltransferase activity IEA
 molecular_functionGO:0004661 protein geranylgeranyltransferase activity IDA
 molecular_functionGO:0004662 CAAX-protein geranylgeranyltransferase activity TAS
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019840 isoprenoid binding IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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