ENSG00000164485


Homo sapiens

Features
Gene ID: ENSG00000164485
  
Biological name :IL22RA2
  
Synonyms : IL22RA2 / interleukin 22 receptor subunit alpha 2 / Q969J5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q23.3
Gene start: 137143820
Gene end: 137173648
  
Corresponding Affymetrix probe sets: 237493_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296979
Ensembl peptide - ENSP00000296980
Ensembl peptide - ENSP00000340920
NCBI entrez gene - 116379     See in Manteia.
OMIM - 606648
RefSeq - NM_181309
RefSeq - NM_052962
RefSeq - NM_181310
RefSeq Peptide - NP_443194
RefSeq Peptide - NP_851826
RefSeq Peptide - NP_851827
swissprot - Q969J5
Ensembl - ENSG00000164485
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il22ra2ENSDARG00000039439Danio rerio
 Q80XF5ENSMUSG00000039760Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL20RA / Q9UHF4 / interleukin 20 receptor subunit alphaENSG0000001640227
Q8N6P7 / IL22RA1 / interleukin 22 receptor subunit alpha 1ENSG0000014267726


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015373  Interferon/interleukin receptor domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0042509 regulation of tyrosine phosphorylation of STAT protein ISS
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space NAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042017 interleukin-22 binding IDA
 molecular_functionGO:0042018 interleukin-22 receptor activity IDA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000127318 IL22 / Q9GZX6 / interleukin 22  / complex / reaction






 

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