ENSG00000142677


Homo sapiens

Features
Gene ID: ENSG00000142677
  
Biological name :IL22RA1
  
Synonyms : IL22RA1 / interleukin 22 receptor subunit alpha 1 / Q8N6P7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.11
Gene start: 24119771
Gene end: 24143121
  
Corresponding Affymetrix probe sets: 220056_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000270800
NCBI entrez gene - 58985     See in Manteia.
OMIM - 605457
RefSeq - NM_021258
RefSeq - XM_011541882
RefSeq Peptide - NP_067081
swissprot - Q8N6P7
Ensembl - ENSG00000142677
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ifnlr1ENSDARG00000087131Danio rerio
 ENSGALG00000004221Gallus gallus
 Q80XZ4ENSMUSG00000037157Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL20RA / Q9UHF4 / interleukin 20 receptor subunit alphaENSG0000001640216
Q969J5 / IL22RA2 / interleukin 22 receptor subunit alpha 2ENSG0000016448512


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015373  Interferon/interleukin receptor domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0004904 interferon receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042015 interleukin-20 binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105397 TYK2 / P29597 / tyrosine kinase 2  / complex / reaction
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000162892 IL24 / Q13007 / interleukin 24  / complex
 ENSG00000174564 IL20RB / Q6UXL0 / interleukin 20 receptor subunit beta  / complex
 ENSG00000127318 IL22 / Q9GZX6 / interleukin 22  / complex / reaction
 ENSG00000179295 PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11  / complex / reaction
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / reaction / complex
 ENSG00000243646 IL10RB / Q08334 / interleukin 10 receptor subunit beta  / reaction / complex
 ENSG00000162891 IL20 / Q9NYY1 / interleukin 20  / complex






 

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